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西地那非海绵体内自我注射导致的缺血性阴茎异常勃起。

Ischemic priapism caused by self intracavernous injection of tadalafil.

作者信息

Wada Naoki, Hatakeyama Tsubasa, Takagi Haruka, Tsunekawa Ryoken, Kobayashi Shin, Nagabuchi Masaya, Kitta Takeya, Kakizaki Hidehiro

机构信息

Department of Renal and Urologic Surgery Asahikawa Medical University Asahikawa Japan.

出版信息

IJU Case Rep. 2024 Jan 27;7(2):169-172. doi: 10.1002/iju5.12695. eCollection 2024 Mar.

Abstract

INTRODUCTION

We present a case of ischemic priapism caused by self intracavernous injection of tadalafil.

CASE PRESENTATION

A 77-year-old man developed priapism due to self-injection of tadalafil into the corpus cavernosum. He presented to our hospital 2 days after the development of priapism and severe penile pain. The blood gas analysis of the corpus cavernosum revealed ischemic priapism. At first, we performed percutaneous distal shunt (T-shunt) and cavernosal irrigation, resulting in slight improvement of penile tumescence. Several hours later, penile tumescence and severe pain reappeared. Bilateral proximal (corpora-spongiosal) shunt was performed under anesthesia again. Penile tumescence was slowly and gradually relieved. His erectile function was declined.

CONCLUSION

We experienced a case of priapism due to self intracavernous administration of tadalafil who needed a proximal shunt to relieve the severe penile pain. This case report may serve as a warning for physicians and patients not to use phosphodiesterase 5 inhibitor inappropriately.

摘要

引言

我们报告一例因自行海绵体内注射他达拉非导致的缺血性阴茎异常勃起病例。

病例介绍

一名77岁男性因自行将他达拉非注射入海绵体而发生阴茎异常勃起。阴茎异常勃起及严重阴茎疼痛出现2天后他前来我院就诊。海绵体血气分析显示为缺血性阴茎异常勃起。起初,我们进行了经皮远端分流术(T型分流术)及海绵体灌洗,阴茎肿胀稍有改善。数小时后,阴茎再次肿胀且疼痛加剧。遂再次在麻醉下行双侧近端(海绵体-尿道海绵体)分流术。阴茎肿胀缓慢逐渐缓解。但其勃起功能下降。

结论

我们遇到一例因自行海绵体内注射他达拉非导致阴茎异常勃起的病例,该患者需要近端分流术来缓解严重的阴茎疼痛。本病例报告可为医生和患者敲响警钟,提醒不要不恰当地使用磷酸二酯酶5抑制剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66cd/10909140/ccaa0815311c/IJU5-7-169-g001.jpg

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