Annaka Hiroki, Nomura Tomonori, Moriyama Hiroshi
Department of Occupational Therapy, Niigata University of Health and Welfare, Niigata, Japan.
Department of Respiratory Medicine, National Hospital Organization, Nishiniigata Chuo Hospital, Niigata, Japan.
Occup Ther Health Care. 2025 Apr;39(2):397-411. doi: 10.1080/07380577.2024.2324256. Epub 2024 Mar 5.
This case-control study examined cognitive function in patients with mild idiopathic pulmonary fibrosis (IPF), in comparison with controls or moderate-to-severe IPF. Ten mild IPF, 10 moderate-to-severe IPF, and 16 controls were enrolled, and performance on seven different cognitive function tests was compared in each group. IPF showed decreased cognitive function compared to controls in verbal memory, cognitive flexibility and information processing speed. As the scores were lower even in mild IPF, this study suggests that cognitive function declines early in the disease process of IPF. Thus, occupational therapy for IPF should require an assessment of cognitive function and assistance appropriate to the client's function.
这项病例对照研究调查了轻度特发性肺纤维化（IPF）患者的认知功能，并与对照组或中重度IPF患者进行比较。研究招募了10名轻度IPF患者、10名中重度IPF患者和16名对照者，并比较了每组在七种不同认知功能测试中的表现。与对照组相比，IPF患者在言语记忆、认知灵活性和信息处理速度方面的认知功能有所下降。由于即使在轻度IPF患者中分数也较低，本研究表明认知功能在IPF疾病过程的早期就会下降。因此，针对IPF的职业治疗应要求对认知功能进行评估，并根据患者的功能提供适当的帮助。
