Division of Liver Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, China.
Division of Liver Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, China.
Asian J Surg. 2024 May;47(5):2138-2143. doi: 10.1016/j.asjsur.2024.02.115. Epub 2024 Mar 5.
Hepatectomy is widely considered a potential treatment for hepatocellular carcinoma (HCC). Unfortunately, one-third of HCC patients have tumor recurrence within 2 years after surgery (early recurrence), accounting for more than 60% of all recurrence patients. Early recurrence is associated with a worse prognosis. Previous studies have shown that microvascular invasion (MVI) is one of the key factors for early recurrence and poor prognosis in patients with HCC after surgery. This paper reviews the latest literature and summarizes the predictors of MVI, the correlation between MVI and early recurrence, the identification of suspicious nodules or subclinical lesions, and the treatment strategies for MVI-positive HCC. The aim is to explore the management of patients with MVI-positive HCC.
肝切除术被广泛认为是治疗肝细胞癌 (HCC) 的一种潜在方法。不幸的是，三分之一的 HCC 患者在手术后 2 年内出现肿瘤复发（早期复发），占所有复发患者的 60%以上。早期复发与预后不良有关。先前的研究表明，微血管侵犯 (MVI) 是手术后 HCC 患者早期复发和预后不良的关键因素之一。本文综述了最新的文献，总结了 MVI 的预测因素、MVI 与早期复发的相关性、可疑结节或亚临床病变的识别以及 MVI 阳性 HCC 的治疗策略。目的是探讨 MVI 阳性 HCC 患者的管理。
