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枸杞基因组数据库:用于研究分子生物学的综合基因组数据集。

Wolfberry genome database: integrated genomic datasets for studying molecular biology.

作者信息

Cao You-Long, Chen You-Yi, Li Yan-Long, Li Chung-I, Lin Shao-Ting, Lee Bing-Ru, Hsieh Chun-Lin, Hsiao Yu-Yun, Fan Yun-Fang, Luo Qing, Zhao Jian-Hua, Yin Yue, An Wei, Shi Zhi-Gang, Chow Chi-Nga, Chang Wen-Chi, Huang Chun-Lin, Chang Wei-Hung, Liu Zhong-Jian, Wu Wei-Sheng, Tsai Wen-Chieh

机构信息

National Wolfberry Engineering Research Center, Ningxia Academy of Agriculture and Forestry Sciences, Yinchuan, China.

Institute of Wolfberry Engineering Technology, Ningxia Academy of Agriculture and Forestry Sciences, Yinchuan, China.

出版信息

Front Plant Sci. 2024 Feb 20;15:1310346. doi: 10.3389/fpls.2024.1310346. eCollection 2024.

Abstract

Wolfberry, also known as goji berry or , is a highly valued fruit with significant health benefits and nutritional value. For more efficient and comprehensive usage of published genomic data, we established the Wolfberry database. The utility of the Wolfberry Genome Database (WGDB) is highlighted through the Genome browser, which enables the user to explore the genome, browse specific chromosomes, and access gene sequences. Gene annotation features provide comprehensive information about gene functions, locations, expression profiles, pathway involvement, protein domains, and regulatory transcription factors. The transcriptome feature allows the user to explore gene expression patterns using transcripts per kilobase million (TPM) and fragments per kilobase per million mapped reads (FPKM) metrics. The Metabolism pathway page provides insights into metabolic pathways and the involvement of the selected genes. In addition to the database content, we also introduce six analysis tools developed for the WGDB. These tools offer functionalities for gene function prediction, nucleotide and amino acid BLAST analysis, protein domain analysis, GO annotation, and gene expression pattern analysis. The WGDB is freely accessible at https://cosbi7.ee.ncku.edu.tw/Wolfberry/. Overall, WGDB serves as a valuable resource for researchers interested in the genomics and transcriptomics of . Its user-friendly web interface and comprehensive data facilitate the exploration of gene functions, regulatory mechanisms, and metabolic pathways, ultimately contributing to a deeper understanding of wolfberry and its potential applications in agronomy and nutrition.

摘要

枸杞,也被称为枸杞果或,是一种具有重要健康益处和营养价值的高价值水果。为了更高效、全面地利用已发表的基因组数据,我们建立了枸杞数据库。枸杞基因组数据库(WGDB)的实用性通过基因组浏览器得以凸显,该浏览器使用户能够探索基因组、浏览特定染色体并访问基因序列。基因注释功能提供了有关基因功能、位置、表达谱、途径参与情况、蛋白质结构域和调控转录因子的全面信息。转录组功能允许用户使用每千碱基百万转录本(TPM)和每百万映射 reads 每千碱基片段数(FPKM)指标来探索基因表达模式。代谢途径页面提供了对代谢途径以及所选基因参与情况的见解。除了数据库内容外,我们还介绍了为 WGDB 开发的六个分析工具。这些工具提供了基因功能预测、核苷酸和氨基酸 BLAST 分析、蛋白质结构域分析、GO 注释和基因表达模式分析等功能。WGDB 可通过 https://cosbi7.ee.ncku.edu.tw/Wolfberry/免费访问。总体而言,WGDB 是对枸杞基因组学和转录组学感兴趣的研究人员的宝贵资源。其用户友好的网络界面和全面的数据便于探索基因功能、调控机制和代谢途径,最终有助于更深入地了解枸杞及其在农学和营养方面的潜在应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45f6/10912414/c94f5fa5288d/fpls-15-1310346-g001.jpg

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