Watjer Roeland M, Eekhof Just Ah, Quint Koen D, Numans Mattijs E, Bonten Tobias N
Department of Public Health and Primary Care, Leiden University Medical Center (LUMC), Leiden, The Netherlands.
Department of Dermatology, Leiden University Medical Center (LUMC), Leiden, The Netherlands.
SAGE Open Med Case Rep. 2024 Mar 4;12:2050313X241235823. doi: 10.1177/2050313X241235823. eCollection 2024.
Onychomycosis is the most prevalent nail disease and is frequently encountered in clinical practice. Despite having multiple therapeutic options, of which systemic antifungals are the most effective, treatment is not always mandatory in all patients. Especially when considering systemic treatment, the risk of adverse reactions may outweigh the potential benefits of treatment. In this case report, we present a clinical case of a 49-year-old male patient with a blank past medical history who experienced a severe drug eruption from terbinafine prescribed for mild onychomycosis that required discontinuation of terbinafine, additional evaluation, and treatment of this adverse reaction.
甲癣是最常见的指甲疾病,在临床实践中经常遇到。尽管有多种治疗选择,其中全身用抗真菌药最为有效,但并非所有患者都必须进行治疗。特别是在考虑全身治疗时,不良反应的风险可能超过治疗的潜在益处。在本病例报告中,我们展示了一名49岁男性患者的临床病例,该患者既往病史空白,因轻度甲癣服用特比萘芬后发生严重药物疹,需要停用特比萘芬、进行进一步评估并治疗这种不良反应。