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利用平面硅衰减全反射在空气和液体中进行底部照明光热纳米级化学成像。

Bottom-Illuminated Photothermal Nanoscale Chemical Imaging with a Flat Silicon ATR in Air and Liquid.

作者信息

Yilmaz Ufuk, Sam Savda, Lendl Bernhard, Ramer Georg

机构信息

Institute of Chemical Technologies and Analytics, TU Wien, Vienna 1060, Austria.

Centre for Advanced Photonics and Process Analysis, Munster Technological University, Cork T12P928, Ireland.

出版信息

Anal Chem. 2024 Mar 19;96(11):4410-4418. doi: 10.1021/acs.analchem.3c04348. Epub 2024 Mar 6.

DOI:10.1021/acs.analchem.3c04348
PMID:38445554
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10955511/
Abstract

We demonstrate a novel approach for bottom-illuminated atomic force microscopy and infrared spectroscopy (AFM-IR). Bottom-illuminated AFM-IR for measurements in liquids makes use of an attenuated total reflection setup where the developing evanescent wave is responsible for photothermal excitation of the sample of interest. Conventional bottom-illuminated measurements are conducted using high-refractive-index prisms. We showcase the advancement of instrumentation through the introduction of flat silicon substrates as replacements for prisms. We illustrate the feasibility of this technique for bottom-illuminated AFM-IR in both air and liquid. We also show how modern rapid prototyping technologies enable commercial AFM-IR instrumentation to accept these new substrates. This new approach paves the way for a wide range of experiments since virtually any established protocol for Si surface functionalization can be applied to this sample carrier. Furthermore, the low unit cost enables the rapid iteration of experiments.

摘要

我们展示了一种用于底部照明原子力显微镜和红外光谱（AFM-IR）的新方法。用于液体测量的底部照明AFM-IR利用衰减全反射装置，其中产生的倏逝波负责对感兴趣的样品进行光热激发。传统的底部照明测量使用高折射率棱镜进行。我们通过引入平面硅基板替代棱镜来展示仪器的进步。我们说明了这种技术在空气和液体中用于底部照明AFM-IR的可行性。我们还展示了现代快速成型技术如何使商用AFM-IR仪器能够接受这些新基板。这种新方法为广泛的实验铺平了道路，因为几乎任何已确立的硅表面功能化方案都可以应用于这种样品载体。此外，单位成本低使得实验能够快速迭代。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/8e01c506a889/ac3c04348_0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/587be678e0b8/ac3c04348_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/5f61c1074534/ac3c04348_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/dc3ffa23e562/ac3c04348_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/04a01bdb7a2e/ac3c04348_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/cdca168ab3d8/ac3c04348_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/0a6174164642/ac3c04348_0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/f4ac692a6c5e/ac3c04348_0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/4c9a439a1e42/ac3c04348_0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/c33bed6fa6e4/ac3c04348_0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/8e01c506a889/ac3c04348_0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/587be678e0b8/ac3c04348_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/5f61c1074534/ac3c04348_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/dc3ffa23e562/ac3c04348_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/04a01bdb7a2e/ac3c04348_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/cdca168ab3d8/ac3c04348_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/0a6174164642/ac3c04348_0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/f4ac692a6c5e/ac3c04348_0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/4c9a439a1e42/ac3c04348_0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/c33bed6fa6e4/ac3c04348_0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65c/10955511/8e01c506a889/ac3c04348_0010.jpg

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