Lépine Charles
Service d'anatomie et cytologie pathologiques, University Hospital Centre Nantes, Nantes université, CHU de Nantes, 44000 Nantes, France; Inserm, INCIT, UMR 1302/EMR6001, CNRS, Immunology and New Concepts in ImmunoTherapy, Nantes, France.
Ann Pathol. 2024 May;44(3):175-182. doi: 10.1016/j.annpat.2024.02.005. Epub 2024 Mar 5.
In 2022, the 5th edition of the WHO classification of Head and Neck tumors was published online. In the salivary gland chapter, a new benign entity, the keratocystoma, was introduced. The sclerosing polycystic adenosis has been recognized as tumoral and is now termed sclerosing polycystic adenoma. The striated duct adenoma now has its own dedicated chapter. Additionally, a new variant of pleomorphic adenoma, termed "canalicular adenoma-like," has been incorporated. Regarding malignant tumors of the salivary glands, significant doubts now exist regarding the actual existence of oncocytic carcinoma, which has been reclassified among emerging entities. Two new malignant entities have also emerged: microsecretory adenocarcinoma and microcystic sclerosing adenocarcinoma. Finally, primary mucinous adenocarcinoma of the salivary glands has been acknowledged as a distinct entity.
2022年，《世界卫生组织头颈部肿瘤分类》第5版在线发布。在唾液腺章节中，引入了一种新的良性病变——角化囊肿瘤。硬化性多囊性腺病已被认定为肿瘤性病变，现称为硬化性多囊性腺瘤。纹管腺瘤现在有了自己独立的章节。此外，还纳入了一种多形性腺瘤的新变体，称为“小管腺瘤样”。关于唾液腺恶性肿瘤，现在对于嗜酸性细胞癌的实际存在存在重大疑问，它已被重新分类到新兴病变中。另外还出现了两种新的恶性病变：微分泌腺癌和微囊性硬化性腺癌。最后，唾液腺原发性黏液腺癌已被确认为一种独特的病变。
