Harada Kei, Fujikawa Takahisa, Matsuoka Taisuke, Uemoto Yusuke, Emoto Norio
Surgery, Kokura Memorial Hospital, Kitakyushu, JPN.
Surgery, Ijinkai Takeda General Hospital, Kyoto, JPN.
Cureus. 2024 Feb 5;16(2):e53657. doi: 10.7759/cureus.53657. eCollection 2024 Feb.
It is well known that portal vein thrombosis (PVT) sometimes occurs in pancreatic cancer (PC). However, no effective treatment plan for PVT in PC patients has yet been proposed. We experienced a successfully treated case of borderline resectable pancreatic cancer (PC-BR) with extensive superior mesenteric vein thrombosis utilizing intensive chemotherapy combined with direct oral anticoagulant. The thrombus disappeared and the tumor shrank, enabling curative surgery, and long-term survival for more than five years has been achieved. We report this successful case that we experienced as an option for the treatment of PC-BR with PVT in the future era when multimodal treatment is important.
众所周知,门静脉血栓形成(PVT)有时会发生在胰腺癌(PC)中。然而,尚未提出针对PC患者PVT的有效治疗方案。我们经历了一例成功治疗的临界可切除胰腺癌(PC-BR)伴广泛肠系膜上静脉血栓形成的病例,采用强化化疗联合直接口服抗凝剂治疗。血栓消失,肿瘤缩小,得以进行根治性手术,并实现了超过五年的长期生存。我们报告这例成功病例,作为未来多模式治疗很重要的时代中治疗伴有PVT的PC-BR的一种选择。