Osborne Olivia J, Boobis Alan, Botham Phil, Price Shirley Christine, Kuhnle Gunter C, Mulholland Cath, Potter Claire, Gott David
Chemical Risk Assessment Team, Science, Evidence and Research Division, Food Standards Agency, Petty France, Westminster, London SW1H 9EX, United Kingdom.
National Heart and Lung Institute, Imperial College London, Du Cane Road, London W12 0NN, United Kingdom.
Toxicol Res (Camb). 2024 Mar 4;13(2):tfae016. doi: 10.1093/toxres/tfae016. eCollection 2024 Apr.
The further optimization of consumer safety through risk assessment of chemicals present in food will require adaptability and flexibility to utilize the accelerating developments in safety science and technology. New Approach Methodologies (NAMs) are gaining traction as a systematic approach to support informed decision making in chemical risk assessment. The vision is to be able to predict risk more accurately, rapidly and efficiently. The opportunity exists now to use these approaches which requires a strategy to translate the science into future regulatory implementation. Here we discuss new insights obtained from three recent workshops on how to translate the science into future regulatory implementation. To assist the UK in this endeavor, the Food Standards Agency (FSA) and the scientific advisory committee on chemical toxicity (COT) have been developing a roadmap. In addition, we discuss how these new insights fit into the bigger picture of the new chemical landscape for better consumer safety and the importance of international harmonization.
通过对食品中存在的化学物质进行风险评估来进一步优化消费者安全，将需要具备适应性和灵活性，以利用安全科学技术领域不断加速的发展。新方法学（NAMs）作为一种支持化学风险评估中明智决策的系统方法正越来越受到关注。其愿景是能够更准确、快速和高效地预测风险。现在有机会使用这些方法，这需要一种将科学转化为未来监管实施的策略。在此，我们讨论从最近三次关于如何将科学转化为未来监管实施的研讨会中获得的新见解。为协助英国开展这项工作，食品标准局（FSA）和化学毒性科学咨询委员会（COT）一直在制定一份路线图。此外，我们还将讨论这些新见解如何融入新化学格局的大背景中，以实现更好的消费者安全以及国际协调的重要性。
