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筛查试验预测心包积液病因中的癌症转移：HALP 评分和 PNI。

Screening Tests Predicting Cancer Metastasis in the Etiology of Pericardial Effusion: HALP Score and PNI.

机构信息

Sivas Cumhuriyet University - Department of Cardiology, Sivas - Turquia.

Usak University - Department of Cardiology, Usak - Turquia.

出版信息

Arq Bras Cardiol. 2024 Mar 4;121(1):e20230376. doi: 10.36660/abc.20230376. eCollection 2024.

DOI:10.36660/abc.20230376
PMID:38451561
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11081201/
Abstract

BACKGROUND

Cancer screening is absolutely necessary in patients with pericardial effusion, given that cancer is one of the most serious diseases in the etiology of pericardial effusion. In previous studies, it was stated that the systemic immune-inflammation index (SII); the prognostic nutrition index (PNI); and the hemoglobin, albumin, lymphocyte, platelet (HALP) score can produce scores related to cancer.

OBJECTIVES

This study began considering that these scoring systems could predict cancer in the etiology of patients with pericardial effusion.

METHODS

This study produced a retrospective analysis of patients who underwent pericardiocentesis between 2006 and 2022. Pericardiocentesis was performed in a total of 283 patients with moderate-to-large pericardial effusion or pericardial tamponade within the specified period. HALP, PNI, and SII scores were calculated according to the peripheral venous blood taken before the pericardiocentesis procedure. The statistical significance level was set at p<0.05.

RESULTS

The HALP score proved to be 0.173 (0.125-0.175) in cancer patients and 0.32 (0.20-0.49) in non-cancer patients (p<0.001). The PNI score proved to be 33.1±5.6 in cancer patients and 39.8±4.8 in non-cancer patients (p<0.001).

CONCLUSION

The HALP score and PNI proved to be easy and fast cancer screening tests that can predict cancer metastasis in the etiology of patients with pericardial effusion.

摘要

背景

由于癌症是心包积液病因学中最严重的疾病之一，因此心包积液患者绝对需要进行癌症筛查。在以前的研究中，有人指出系统免疫炎症指数（SII）；预后营养指数（PNI）；以及血红蛋白、白蛋白、淋巴细胞、血小板（HALP）评分可以产生与癌症相关的评分。

目的

本研究开始考虑这些评分系统是否可以预测心包积液病因学中的癌症。

方法

本研究对 2006 年至 2022 年间接受心包穿刺术的患者进行了回顾性分析。在规定的时间内，共有 283 例中等量至大量心包积液或心包填塞的患者接受了心包穿刺术。根据心包穿刺术前采集的外周静脉血计算 HALP、PNI 和 SII 评分。统计显著性水平设为 p<0.05。

结果

癌症患者的 HALP 评分为 0.173（0.125-0.175），非癌症患者的 HALP 评分为 0.32（0.20-0.49）（p<0.001）。癌症患者的 PNI 评分为 33.1±5.6，非癌症患者的 PNI 评分为 39.8±4.8（p<0.001）。

结论

HALP 评分和 PNI 被证明是简单快速的癌症筛查试验，可以预测心包积液病因学中的癌症转移。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7525/11081201/eabd423ceb82/0066-782X-abc-121-01-e20230376-gf01-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7525/11081201/4d07c207a118/0066-782X-abc-121-01-e20230376-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7525/11081201/abab64816189/0066-782X-abc-121-01-e20230376-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7525/11081201/c5f3c6697165/0066-782X-abc-121-01-e20230376-gf02-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7525/11081201/eabd423ceb82/0066-782X-abc-121-01-e20230376-gf01-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7525/11081201/4d07c207a118/0066-782X-abc-121-01-e20230376-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7525/11081201/abab64816189/0066-782X-abc-121-01-e20230376-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7525/11081201/c5f3c6697165/0066-782X-abc-121-01-e20230376-gf02-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7525/11081201/eabd423ceb82/0066-782X-abc-121-01-e20230376-gf01-en.jpg

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本文引用的文献

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