Universidade Federal de Pernambuco, Recife, PE, Brazil.
Arq Bras Oftalmol. 2024 Mar 4;87(2):e20220336. doi: 10.5935/0004-2749.2022-0336. eCollection 2024.
To compare the injection of small amounts of undiluted C3F8 with the traditional gas injection in vitrectomy for macular hole treatment.
This clinical trial included 26 individuals divided into two groups. Group 1 received an intravitreal injection of 0.9-1.0 mL of 100% C3F8, and Group 2 received 15-20 mL of 20% C3F8.
The median intraocular gas duration was 31 days in Group 1 and 34 in Group 2. The median letter gains in corrected distance visual acuity for the 26th postoperative week were 20 letters in Group 1 and 12.5 in Group 2. The median intraocular pressure was normal in both groups. Primary anatomical success was 11/13 in both groups.
The use of C3F8 gas in a small undiluted volume is an alternative that slightly reduces the duration of the gas without negatively affecting the anatomical and visual response.
比较在治疗黄斑裂孔的玻璃体切割术中注射小剂量未稀释的 C3F8 与传统气体注射的效果。
本临床试验纳入了 26 名患者，分为两组。第 1 组接受了 0.9-1.0ml 的 100% C3F8 眼内注射，第 2 组接受了 15-20ml 的 20% C3F8 眼内注射。
第 1 组的眼内气体持续时间中位数为 31 天，第 2 组为 34 天。术后第 26 周时，矫正视力的平均字母数增益在第 1 组为 20 个字母，在第 2 组为 12.5 个字母。两组的平均眼内压均正常。两组的主要解剖成功率均为 11/13。
使用小体积未稀释的 C3F8 气体是一种替代方案，可略微缩短气体持续时间，而不会对解剖和视觉反应产生负面影响。
