Department of Pediatrics, The University of Tennessee Health Science Center, Memphis, Tennessee, USA
Department of Pediatrics, University of Padua, Padua, Italy.
Arch Dis Child Educ Pract Ed. 2024 Sep 19;109(5):247-251. doi: 10.1136/archdischild-2023-325938.
Immunoglobulin E (IgE)-mediated food allergy is an immune response, typically to a food protein. Accurate diagnosis reduces unnecessary dietary restrictions and economic and psychological burden on patients and caregivers but relies on a rigorous clinical history, specific IgE diagnostic tests and, where needed, oral food challenge. Increased awareness is needed around which patients to test for IgE-mediated food allergy, as well as terms commonly associated with IgE-mediated food allergy testing, in order to optimise patient diagnosis and management. Herein, we describe approaches to diagnosis of IgE-mediated food allergy, appropriate interpretation of results and risks of overtesting.
免疫球蛋白 E（IgE）介导的食物过敏是一种免疫反应，通常针对食物蛋白。准确的诊断可减少不必要的饮食限制，减轻患者和护理人员的经济和心理负担，但需要严格的临床病史、特异性 IgE 诊断检测，在必要时还需要进行口服食物激发试验。需要提高对哪些患者进行 IgE 介导的食物过敏检测的认识，以及与 IgE 介导的食物过敏检测相关的常用术语，以优化患者的诊断和管理。在此，我们描述了 IgE 介导的食物过敏的诊断方法、结果的合理解读以及过度检测的风险。
