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[复杂原发性肺肉瘤样癌的多领域综合治疗策略病例]

[A Case of Multidomain Integrated Treatment Strategy 
for Complex Primary Pulmonary Sarcomatoid Carcinoma].

作者信息

Huo Xiaosen, Zou Hang, Dong Yanyan, Li Yuan, Bian Lingjie, Li Lei, Wang Hongwu

机构信息

Respiratory Disease Center, Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 101121, China.

出版信息

Zhongguo Fei Ai Za Zhi. 2024 Feb 20;27(2):157-160. doi: 10.3779/j.issn.1009-3419.2024.102.04.

DOI:10.3779/j.issn.1009-3419.2024.102.04
PMID:38453449
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10918249/
Abstract

Pulmonary sarcomatoid carcinoma (PSC) is a rare and highly malignant tumor, which includes the following five pathologic types: pleomorphic carcinoma, spindle cell carcinoma, giant cell carcinoma, carcinosarcoma and pulmonary blastoma. The onset of PSC is occult with non-specific clinical symptoms and signs. The clinical manifestations include irritating cough, bloody sputum, dyspnea, chest pain and so on, which are closely related to the growth and invasion site of the tumor. PSC tends to metastasize early, so most patients are already in local advanced stage or advanced stage with a median survival of 9 months at the time of hospital visit. A patient with primary PSC which led to 90% stenosis in central airway was treated by combined method of vascular and tracheoscopic intervention in our respiratory center. This treatment prolonged the patient's survival time and got a satisfactory effect at 19-month follow-up after surgery. Herein we report the case for clinical reference.
.

摘要

肺肉瘤样癌(PSC)是一种罕见的高恶性肿瘤,包括以下五种病理类型:多形性癌、梭形细胞癌、巨细胞癌、癌肉瘤和肺母细胞瘤。PSC起病隐匿,临床症状和体征不具特异性。临床表现包括刺激性咳嗽、咯血、呼吸困难、胸痛等,这些与肿瘤的生长和侵犯部位密切相关。PSC往往早期发生转移,因此大多数患者就诊时已处于局部晚期或晚期,中位生存期为9个月。我院呼吸中心采用血管介入与气管镜介入联合方法治疗了1例导致中央气道90%狭窄的原发性PSC患者。该治疗延长了患者的生存时间,术后19个月随访效果满意。在此报告该病例以供临床参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f9/10918249/5e766f7c36f5/img_3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f9/10918249/ccb37c4f4608/img_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f9/10918249/132327131eaf/img_2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f9/10918249/5e766f7c36f5/img_3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f9/10918249/ccb37c4f4608/img_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f9/10918249/132327131eaf/img_2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f9/10918249/5e766f7c36f5/img_3.jpg

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2
The Prognosis of Pulmonary Sarcomatoid Carcinoma: Development and Validation of a Nomogram Based on SEER.肺肉瘤样癌的预后:基于 SEER 的列线图的建立与验证。
Technol Cancer Res Treat. 2022 Jan-Dec;21:15330338221109647. doi: 10.1177/15330338221109647.
3
Clinicopathological characteristics and prognostic factors of pulmonary sarcomatoid carcinoma: a large population analysis.
肺肉瘤样癌的临床病理特征及预后因素:一项大样本分析
Ann Transl Med. 2021 Jan;9(2):121. doi: 10.21037/atm-20-6213.
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Pulmonary Sarcomatoid Carcinoma: Experience From SEER Database and Shanghai Pulmonary Hospital.肺肉瘤样癌:SEER 数据库和上海肺科医院的经验。
Ann Thorac Surg. 2020 Aug;110(2):406-413. doi: 10.1016/j.athoracsur.2020.02.071. Epub 2020 Apr 5.
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Approaches to Tumor Classification in Pulmonary Sarcomatoid Carcinoma.肺肉瘤样癌的肿瘤分类方法
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6
F-FDG PET/CT imaging in pulmonary sarcomatoid carcinoma and correlation with clinical and genetic findings.氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描成像在肺肉瘤样癌中的应用及与临床和遗传学发现的相关性。
Ann Nucl Med. 2019 Sep;33(9):647-656. doi: 10.1007/s12149-019-01374-5. Epub 2019 Jun 5.
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