Huo Xiaosen, Zou Hang, Dong Yanyan, Li Yuan, Bian Lingjie, Li Lei, Wang Hongwu
Respiratory Disease Center, Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 101121, China.
Zhongguo Fei Ai Za Zhi. 2024 Feb 20;27(2):157-160. doi: 10.3779/j.issn.1009-3419.2024.102.04.
Pulmonary sarcomatoid carcinoma (PSC) is a rare and highly malignant tumor, which includes the following five pathologic types: pleomorphic carcinoma, spindle cell carcinoma, giant cell carcinoma, carcinosarcoma and pulmonary blastoma. The onset of PSC is occult with non-specific clinical symptoms and signs. The clinical manifestations include irritating cough, bloody sputum, dyspnea, chest pain and so on, which are closely related to the growth and invasion site of the tumor. PSC tends to metastasize early, so most patients are already in local advanced stage or advanced stage with a median survival of 9 months at the time of hospital visit. A patient with primary PSC which led to 90% stenosis in central airway was treated by combined method of vascular and tracheoscopic intervention in our respiratory center. This treatment prolonged the patient's survival time and got a satisfactory effect at 19-month follow-up after surgery. Herein we report the case for clinical reference. .
肺肉瘤样癌(PSC)是一种罕见的高恶性肿瘤,包括以下五种病理类型:多形性癌、梭形细胞癌、巨细胞癌、癌肉瘤和肺母细胞瘤。PSC起病隐匿,临床症状和体征不具特异性。临床表现包括刺激性咳嗽、咯血、呼吸困难、胸痛等,这些与肿瘤的生长和侵犯部位密切相关。PSC往往早期发生转移,因此大多数患者就诊时已处于局部晚期或晚期,中位生存期为9个月。我院呼吸中心采用血管介入与气管镜介入联合方法治疗了1例导致中央气道90%狭窄的原发性PSC患者。该治疗延长了患者的生存时间,术后19个月随访效果满意。在此报告该病例以供临床参考。