• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

患者血液管理对转移性脊柱肿瘤手术的结果有影响吗?当前概念综述。

Does Patient Blood Management Affect Outcomes in Metastatic Spine Tumour Surgery? A Review of Current Concepts.

作者信息

Kumar Naresh, Lee Eunice Xin Yi, Hui Si Jian, Kumar Laranya, Jonathan Tan Jiong Hao, Ashokka Balakrishnan

机构信息

University Spine Centre, Department of Orthopaedic Surgery, National University Health System, Singapore.

Department of Anaesthesia, National University Hospital, Singapore.

出版信息

Global Spine J. 2024 Mar 7:21925682231167096. doi: 10.1177/21925682231167096.

DOI:10.1177/21925682231167096
PMID:38453667
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11572015/
Abstract

STUDY DESIGN

Narrative review.

OBJECTIVE

The spine is the most common site of metastases, associated with decreased quality of life. Increase in metastatic spine tumour surgery (MSTS) has caused us to focus on the management of blood, as blood loss is a significant morbidity in these patients. However, blood transfusion is also not without its own risks, and hence this led to blood conservation strategies and implementation of a concept of patient blood management (PBM) in clinical practise focusing on these patients.

METHODS

A narrative review was conducted and all studies that were related to blood management in metastatic spine disease as well as PBM surrounding this condition were included.

RESULTS

A total of 64 studies were included in this review. We discussed a new concept of patient blood management in patients undergoing MSTS, with stratification to pre-operative and intra-operative factors, as well as anaesthesia and surgical considerations. The studies show that PBM and reduction in blood transfusion allows for reduced readmission rates, lower risks associated with blood transfusion, and lower morbidity for patients undergoing MSTS.

CONCLUSION

Through this review, we highlight various pre-operative and intra-operative methods in the surgical and anaesthesia domains that can help with PBM. It is an important concept with the significant amount of blood loss expected from MSTS.

LEVEL OF EVIDENCE

Not applicable.

摘要

研究设计

叙述性综述。

目的

脊柱是最常见的转移部位,与生活质量下降相关。转移性脊柱肿瘤手术(MSTS)的增加使我们将重点放在血液管理上,因为失血是这些患者的一项重大发病因素。然而,输血也并非没有自身风险,因此这促使在临床实践中针对这些患者制定血液保护策略并实施患者血液管理(PBM)概念。

方法

进行了一项叙述性综述,纳入了所有与转移性脊柱疾病血液管理以及围绕该病症的PBM相关的研究。

结果

本综述共纳入64项研究。我们讨论了接受MSTS患者的患者血液管理新概念,对术前和术中因素以及麻醉和手术考量进行了分层。研究表明,PBM和减少输血可降低再次入院率、降低与输血相关的风险,并降低接受MSTS患者的发病率。

结论

通过本综述,我们强调了手术和麻醉领域中有助于PBM的各种术前和术中方法。鉴于MSTS预计会有大量失血,这是一个重要概念。

证据水平

不适用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1466/11572015/9d105ef2ffcf/10.1177_21925682231167096-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1466/11572015/9d105ef2ffcf/10.1177_21925682231167096-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1466/11572015/9d105ef2ffcf/10.1177_21925682231167096-fig1.jpg

相似文献

1
Does Patient Blood Management Affect Outcomes in Metastatic Spine Tumour Surgery? A Review of Current Concepts.患者血液管理对转移性脊柱肿瘤手术的结果有影响吗?当前概念综述。
Global Spine J. 2024 Mar 7:21925682231167096. doi: 10.1177/21925682231167096.
2
The safety, efficacy, and cost-effectiveness of intraoperative cell salvage in metastatic spine tumor surgery.转移性脊柱肿瘤手术中术中细胞回收的安全性、有效性和成本效益。
Spine J. 2017 Jul;17(7):977-982. doi: 10.1016/j.spinee.2017.03.004. Epub 2017 Mar 18.
3
Intraoperative cell-salvaged autologous blood transfusion is safe in metastatic spine tumour surgery: early outcomes of prospective clinical study.术中细胞回收式自体输血在转移性脊柱肿瘤手术中是安全的:前瞻性临床研究的早期结果。
Eur Spine J. 2023 Jul;32(7):2493-2502. doi: 10.1007/s00586-023-07768-4. Epub 2023 May 16.
4
Peri-operative blood management.围手术期血液管理
Indian J Anaesth. 2017 Jun;61(6):456-462. doi: 10.4103/ija.IJA_341_17.
5
The impact of patient blood management on blood utilization and clinical outcomes in complex spine surgery.患者血液管理对复杂脊柱手术中血液利用和临床结局的影响。
Transfusion. 2019 Dec;59(12):3639-3645. doi: 10.1111/trf.15544. Epub 2019 Oct 18.
6
Implant and construct decision-making in metastatic spine tumour surgery: a review of current concepts with a decision-making algorithm.脊柱转移瘤手术中的植入物和构建决策:当前概念的综述及决策算法。
Eur Spine J. 2024 May;33(5):1899-1910. doi: 10.1007/s00586-023-07987-9. Epub 2024 Jan 30.
7
Transfusion guidelines in adult spine surgery: a systematic review and critical summary of currently available evidence.成人脊柱手术中的输血指南:对当前可用证据的系统评价与批判性总结
Spine J. 2022 Feb;22(2):238-248. doi: 10.1016/j.spinee.2021.07.018. Epub 2021 Jul 31.
8
Patient Blood Management During Lumbar Spinal Fusion Surgery.患者血液管理在腰椎融合手术中的应用。
World Neurosurg. 2019 Oct;130:e566-e572. doi: 10.1016/j.wneu.2019.06.153. Epub 2019 Jun 26.
9
Perioperative paediatric patient blood management: a narrative review.围手术期儿科患者血液管理:一篇叙述性综述。
Br J Anaesth. 2025 Jan;134(1):168-179. doi: 10.1016/j.bja.2024.08.034. Epub 2024 Oct 24.
10
Are we ready for the use of intraoperative salvaged blood in metastatic spine tumour surgery?我们是否准备好在转移性脊柱肿瘤手术中使用术中回收血?
Eur Spine J. 2016 Dec;25(12):3997-4007. doi: 10.1007/s00586-015-4112-x. Epub 2015 Jul 19.

引用本文的文献

1
Safety and efficacy of tranexamic acid in oncologic surgery for spinal metastases: A systematic review.氨甲环酸在脊柱转移瘤肿瘤手术中的安全性和有效性:一项系统评价。
N Am Spine Soc J. 2025 Apr 23;22:100613. doi: 10.1016/j.xnsj.2025.100613. eCollection 2025 Jun.
2
When Would Minimally Invasive Spinal Surgery Not Be Preferable for Metastatic Spine Disease?对于转移性脊柱疾病,何时微创脊柱手术并非首选?
Int J Spine Surg. 2024 Nov 15;18(6):738-44. doi: 10.14444/8658.

本文引用的文献

1
Corrigendum to 'Patient blood management and perioperative anaemia' [ 17 (2017) 28-34].《患者血液管理与围手术期贫血》[17 (2017) 28 - 34]的勘误
BJA Educ. 2024 Mar;24(3):107. doi: 10.1016/j.bjae.2023.12.001. Epub 2024 Jan 12.
2
Posterior Percutaneous Pedicle Screws Fixation Versus Open Surgical Instrumented Fusion for Thoraco-Lumbar Spinal Metastases Palliative Management: A Systematic Review and Meta-analysis.经皮后路椎弓根螺钉固定术与开放手术器械融合术治疗胸腰椎脊柱转移瘤姑息治疗的系统评价和荟萃分析
Front Oncol. 2022 Apr 4;12:884928. doi: 10.3389/fonc.2022.884928. eCollection 2022.
3
Single-Surgeon Versus Dual-Surgeon Strategy in Spinal Tumor Surgery: A Single Institution Experience.
单术者与双术者策略在脊柱肿瘤手术中的应用:单中心经验
Clin Spine Surg. 2022 Jul 1;35(6):E566-E570. doi: 10.1097/BSD.0000000000001302. Epub 2022 Mar 10.
4
Preoperative embolization in surgical treatment of spinal metastases originating from non-hypervascular primary tumors: a propensity score matched study using 495 patients.术前栓塞在非富血供原发性肿瘤脊柱转移瘤外科治疗中的应用:一项使用 495 例患者的倾向评分匹配研究。
Spine J. 2022 Aug;22(8):1334-1344. doi: 10.1016/j.spinee.2022.03.001. Epub 2022 Mar 6.
5
A Global Definition of Patient Blood Management.患者血液管理全球定义。
Anesth Analg. 2022 Sep 1;135(3):476-488. doi: 10.1213/ANE.0000000000005873. Epub 2022 Feb 10.
6
Analysis of Short-Term versus Long-Term Readmission-Free Survival After Metastatic Spine Tumor Surgery.转移性脊柱肿瘤手术后短期与长期无再入院生存率分析。
World Neurosurg. 2022 Feb;158:e946-e955. doi: 10.1016/j.wneu.2021.11.119. Epub 2021 Dec 1.
7
Adjunctive Topical Tranexamic Acid for Blood Salvage Does Not Reduce Postoperative Blood Loss Compared with Placebo in Patients Who Undergo Palliative Decompressive Spinal Metastasis Surgery: A Randomized Controlled Trial.辅助局部使用氨甲环酸进行血液回收与安慰剂相比并不能减少接受姑息性减压脊柱转移手术患者的术后失血:一项随机对照试验。
Spine (Phila Pa 1976). 2022 Feb 1;47(3):187-194. doi: 10.1097/BRS.0000000000004280.
8
Influence of tranexamic acid use on venous thromboembolism risk in patients undergoing surgery for spine tumors.氨甲环酸的使用对脊柱肿瘤手术患者静脉血栓栓塞风险的影响。
J Neurosurg Spine. 2021 Aug 13;35(5):663-673. doi: 10.3171/2021.1.SPINE201935. Print 2021 Nov 1.
9
Effectiveness of Preoperative Embolization in Patients with Spinal Metastases: A Systematic Review and Meta-Analysis.术前栓塞治疗脊柱转移瘤的疗效:系统评价和荟萃分析。
World Neurosurg. 2021 Aug;152:e745-e757. doi: 10.1016/j.wneu.2021.06.062. Epub 2021 Jun 18.
10
Trends in Utilization of Preoperative Embolization for Spinal Metastases: A Study of the National Inpatient Sample 2005-2017.脊柱转移瘤术前栓塞术的应用趋势:一项基于2005 - 2017年全国住院患者样本的研究
Neurointervention. 2021 Mar;16(1):52-58. doi: 10.5469/neuroint.2020.00381. Epub 2021 Feb 4.