Filho Adalberto M, Warnakulasuriya Saman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.
King's College London, London, UK.
Oral Dis. 2024 Nov;30(8):4847-4854. doi: 10.1111/odi.14906. Epub 2024 Mar 7.
This study provides an epidemiological description of cancer in the lip, oral cavity, and oropharynx in the South and South-East Asia region.
The number of new cases and deaths was extracted from the GLOBOCAN 2020 and the CI5 series. We present age-standardized incidence and mortality rates per 100,000 inhabitants. To assess temporal trends, we estimated the annual percent change.
The incidence rates (ASR) for lip and oral cavity cancer in South and South-East Asia were highest in Taiwan (30.2), Sri Lanka (16.5), India (14.8), and Pakistan (13.2) among males. For oropharyngeal cancer, the highest rates were found in Taiwan (4.7), Bangladesh, Sri Lanka, and India (4.3, 2.9, and 2.6, respectively). Incidence rates were consistently higher in males compared to females. Overall, trends in lip and oral cavity cancer incidence were either stable or decreasing in most of the populations evaluated. In India, an increase in rates among males contrasted with a decline among females over the study period.
Incidence and mortality rates of oral cavity cancer in South and South-East Asia are among the highest globally. Our results suggest an optimistic trend of reduction in oral cavity rates in the region, despite an increase in rates among Indian males.
本研究对南亚和东南亚地区唇、口腔和口咽癌进行了流行病学描述。
从全球癌症统计数据2020版（GLOBOCAN 2020）和CI5系列中提取新发病例数和死亡数。我们呈现了每10万居民的年龄标准化发病率和死亡率。为评估时间趋势，我们估算了年度百分比变化。
南亚和东南亚地区男性唇癌和口腔癌的发病率（年龄标准化率）在台湾地区最高（30.2），其次是斯里兰卡（16.5）、印度（14.8）和巴基斯坦（13.2）。口咽癌发病率最高的地区是台湾（4.7）、孟加拉国、斯里兰卡和印度（分别为4.3、2.9和2.6）。男性发病率始终高于女性。总体而言，在大多数评估人群中，唇癌和口腔癌发病率趋势稳定或呈下降趋势。在印度，研究期间男性发病率上升，而女性发病率下降。
南亚和东南亚地区口腔癌的发病率和死亡率在全球位居前列。我们的结果表明，尽管印度男性发病率有所上升，但该地区口腔癌发病率呈下降趋势，令人乐观。
