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生活目的与认知健康:一项28年的前瞻性研究。

Purpose in life and cognitive health: a 28-year prospective study.

作者信息

Sutin Angelina R, Luchetti Martina, Stephan Yannick, Terracciano Antonio

机构信息

Florida State University College of Medicine, Tallahassee, FL, USA.

Euromov, University of Montpellier, Montpellier, France.

出版信息

Int Psychogeriatr. 2024 Oct;36(10):956-964. doi: 10.1017/S1041610224000383. Epub 2024 Mar 8.

DOI:10.1017/S1041610224000383
PMID:38454883
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11380700/
Abstract

OBJECTIVES

To examine the prospective association between purpose in life measured at three points across middle and older adulthood and cognitive outcomes assessed 8-28 years later.

DESIGN

Prospective Study.

SETTING

Wisconsin Longitudinal Study of Aging (WLS).

PARTICIPANTS

WLS participants who reported on their purpose in life at Round 4 (1992-1994; = 52.58), Round 5 (2003-2007; = 63.74), and/or Round 6 (2010-2012; = 70.25) and were administered a cognitive battery at Round 7 (2020; = 79.94) were included in the analysis ( = 4,632).

MEASUREMENTS

Participants completed the Ryff measure of purpose in life and were administered the telephone interview for cognitive status and measures of verbal fluency, digit ordering, and numeric reasoning.

RESULTS

Purpose in life measured at age 52 was related to better global cognitive function and verbal fluency but unrelated to dementia at age 80. In contrast, purpose in life at ages 63-70 was associated with lower likelihood of dementia, as well as better global cognitive function and verbal fluency at age 80. The effect sizes were modest (median Beta coefficient = .05; median odds ratio = .85). A slightly steeper decline in purpose in life between ages 52 and 70 was found for individuals with dementia at age 80.

CONCLUSIONS

Purpose in life is associated with healthier cognitive function measured up to 28 years later. Individuals with lower purpose, especially in their 60s or older, and with steeper declines in purpose, are more likely to have dementia at age 80.

摘要

目的

研究成年中期和老年期三个时间点所测量的生活目的与8至28年后评估的认知结果之间的前瞻性关联。

设计

前瞻性研究。

背景

威斯康星老龄化纵向研究(WLS)。

参与者

威斯康星老龄化纵向研究的参与者,他们在第4轮(1992 - 1994年;平均年龄52.58岁)、第5轮(2003 - 2007年;平均年龄63.74岁)和/或第6轮(2010 - 2012年;平均年龄70.25岁)报告了他们的生活目的,并在第7轮(2020年;平均年龄79.94岁)接受了认知测试,分析纳入了4632名参与者。

测量方法

参与者完成了生活目的的赖夫量表,并接受了认知状态电话访谈以及语言流畅性、数字排序和数字推理测试。

结果

52岁时测量的生活目的与更好的整体认知功能和语言流畅性相关,但与80岁时的痴呆症无关。相比之下,63 - 70岁时的生活目的与患痴呆症的可能性较低以及80岁时更好的整体认知功能和语言流畅性相关。效应量适中(中位数β系数 = 0.05;中位数优势比 = 0.85)。80岁患痴呆症的个体在52岁至70岁之间生活目的下降幅度略大。

结论

生活目的与长达28年后测量的更健康的认知功能相关。生活目的较低的个体,尤其是60多岁及以上且生活目的下降幅度较大的个体,在80岁时患痴呆症的可能性更大。

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