Descatha Alexis, Fadel Marc, Sembajwe Grace, Peters Susan, Evanoff Bradley A
Univ Angers, CHU Angers, Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail)-UMR_S 1085, SFR ICAT, Angers, France.
CHU Angers, Poisoning Control Center-Clinical Data Center, Angers, France.
Front Epidemiol. 2022 Apr 26;2:857316. doi: 10.3389/fepid.2022.857316. eCollection 2022.
Workplace exposures to physical, chemical, and psychosocial factors account for a large burden of chronic diseases. Obtaining useful estimates of current and past workplace exposures is challenging, particularly in large general population studies. Job-exposure matrices (JEMs) are a useful tool for exposure assessment, particularly when no individual level exposure data are available. A JEM provides a cross-tabulation of job titles (sometimes combined with industry) and estimated exposures to workers carrying out these jobs during different time periods. The major limitation of JEMs is that they do not account for individual variation in exposures within the same job. This limitation is offset by the advantages of low cost, wide applicability, lack of bias from self-reporting, and the ability to estimate exposures based on job titles when no other exposure data exist. There is growing use of JEMs in research examining the role of workplace exposures in the development of chronic diseases, and interest in their application to public health practice. This paper provides a scoping review of JEM use, some examples of JEMs, and brief guidance for the application of JEMs in epidemiological research. In conclusion, JEMs provide a useful tool for researchers and public health practitioners to estimate occupational exposures in large scale epidemiological studies relevant to many health conditions.
工作场所接触物理、化学和社会心理因素是慢性病的一个主要负担来源。获取当前和过去工作场所接触情况的有效估计具有挑战性,尤其是在大型普通人群研究中。职业接触矩阵(JEMs)是暴露评估的一个有用工具,特别是在没有个体水平暴露数据的情况下。JEM提供了一份工作头衔(有时结合行业)与在不同时间段从事这些工作的工人的估计接触情况的交叉列表。JEM的主要局限性在于它们没有考虑同一工作中接触情况的个体差异。这种局限性被低成本、广泛适用性、无自我报告偏差以及在没有其他暴露数据时根据工作头衔估计暴露情况的能力等优点所抵消。在研究工作场所接触在慢性病发展中的作用时,JEM在研究中的应用越来越多,并且人们对其应用于公共卫生实践也很感兴趣。本文对JEM的使用进行了范围界定审查,给出了一些JEM的示例,并为JEM在流行病学研究中的应用提供了简要指导。总之,JEM为研究人员和公共卫生从业者在与多种健康状况相关的大规模流行病学研究中估计职业暴露提供了一个有用的工具。