Wang Wei-Zhen, Wang Qiang, He Xinglei, Shen Yi-Han, Zhai Zi'ang, Zhang Ruiying, Li Yuanming, Ye Ke-Yin
Key Laboratory of Molecule Synthesis and Function Discovery (Fujian Province University), College of Chemistry, Fuzhou University, Fuzhou 350108, China.
Org Lett. 2024 Mar 22;26(11):2243-2248. doi: 10.1021/acs.orglett.4c00445. Epub 2024 Mar 8.
The preparation of polycyclic aromatic hydrocarbons (PAHs) by the Scholl reaction is typically performed by using superstoichiometric oxidants. Herein, we develop an electrochemical continuous-flow Scholl reaction to access PAHs that features a reduction in the use of supporting electrolytes and easy scale-up without changing the reaction conditions and setups. This reaction allows the synthesis of distorted PAHs containing three [5]helicene units that possess intriguing electronic and optical properties.
通过肖尔反应制备多环芳烃（PAHs）通常使用化学计量过量的氧化剂来进行。在此，我们开发了一种电化学连续流肖尔反应来制备多环芳烃，其特点是减少了支持电解质的使用，并且在不改变反应条件和装置的情况下易于放大规模。该反应能够合成含有三个[5]螺旋烯单元的扭曲多环芳烃，这些多环芳烃具有引人入胜的电子和光学性质。
