National Skin Center, Singapore, Singapore ; and.
Lee Kong Chian School of Medicine, Singapore, Singapore .
Am J Dermatopathol. 2024 Jul 1;46(7):452-454. doi: 10.1097/DAD.0000000000002649. Epub 2024 Mar 8.
Hydrophilic polymer embolism from vascular medical devices is an underrecognized clinical entity that can cause deleterious end-organ ischemia and culminate in mortality. This is concerning as we are in the era where minimally invasive procedures are commonplace. Diagnosis is often made retrospectively after obtaining histopathological tissue samples showing endoluminal, cerebriform, amorphous, anucleate, basophilic, nonrefractile, nonpolarizable foreign body material. We detail 2 more cases of cutaneous hydrophilic polymer embolism to underscore its salient clinicopathological features and increase awareness of this important iatrogenic entity.
血管内医疗器械引起的亲水性聚合物栓塞是一种未被充分认识的临床实体,可导致终末器官有害性缺血,并最终导致死亡。鉴于微创介入治疗已广泛应用于临床,这一点尤其令人担忧。在获得显示腔内、脑回状、无定形、无核、嗜碱性、不可折射、非极化的异物材料的组织病理学样本后,通常是回顾性诊断。我们详细描述了另外 2 例皮肤亲水性聚合物栓塞病例,以强调其显著的临床病理特征,并提高对这种重要医源性实体的认识。