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裸鼹鼠的卵巢允许在单个样本中研究卵巢储备、体外生殖细胞扩增和卵母细胞体外成熟。

Naked mole rat ovaries allow investigation of ovarian reserve, in vitro germ cell expansion, and oocyte in vitro maturation within a single sample.

机构信息

Magee-Womens Research Institute, Department of Obstetrics, Gynecology & Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada.

出版信息

Reproduction. 2024 Apr 17;167(5). doi: 10.1530/REP-23-0459. Print 2024 May 1.

DOI:10.1530/REP-23-0459
PMID:38457920
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11023744/
Abstract

Recently, we described that in the naked mole rat ovary it is possible to study the ovarian reserve and the mitotic expansion of the germ cell postnatally. Herein, we show oocyte in vitro maturation and in vitro germ cell expansion using the same ovary.

摘要

最近，我们描述了在裸鼹鼠的卵巢中，可以研究出生后卵巢储备和生殖细胞的有丝分裂扩增。在这里，我们使用相同的卵巢展示了卵母细胞的体外成熟和体外生殖细胞扩增。

相似文献

1
Naked mole rat ovaries allow investigation of ovarian reserve, in vitro germ cell expansion, and oocyte in vitro maturation within a single sample.裸鼹鼠的卵巢允许在单个样本中研究卵巢储备、体外生殖细胞扩增和卵母细胞体外成熟。
Reproduction. 2024 Apr 17;167(5). doi: 10.1530/REP-23-0459. Print 2024 May 1.
2
Characterization of the Postnatal Naked Mole-Rat Ovary: From Primordial Germ Cells to Meiotic Prophase I Oocytes.描述产后裸鼹鼠卵巢：从原始生殖细胞到减数分裂前期 I 卵母细胞。
Methods Mol Biol. 2023;2677:185-201. doi: 10.1007/978-1-0716-3259-8_11.
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Germ cell nests in adult ovaries and an unusually large ovarian reserve in the naked mole-rat.成年裸鼹鼠卵巢中的生殖细胞巢和异常大的卵巢储备。
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本文引用的文献

1
Postnatal oogenesis leads to an exceptionally large ovarian reserve in naked mole-rats.产后卵发生导致裸鼹鼠具有异常大的卵巢储备。
Nat Commun. 2023 Feb 21;14(1):670. doi: 10.1038/s41467-023-36284-8.
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Molecular basis of reproductive senescence: insights from model organisms.生殖衰老的分子基础：来自模式生物的见解
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Chromosome errors in human eggs shape natural fertility over reproductive life span.人类卵子中的染色体错误影响生殖寿命期间的自然生育能力。
Science. 2019 Sep 27;365(6460):1466-1469. doi: 10.1126/science.aav7321.
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Naked Mole-Rat mortality rates defy gompertzian laws by not increasing with age.裸鼹鼠的死亡率与冈珀茨定律相悖，并不会随着年龄的增长而增加。
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Human oocytes. Error-prone chromosome-mediated spindle assembly favors chromosome segregation defects in human oocytes.人类卵母细胞。易出错的染色体介导的纺锤体组装有利于人类卵母细胞中的染色体分离缺陷。
Science. 2015 Jun 5;348(6239):1143-7. doi: 10.1126/science.aaa9529.
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Sperm structure and motility in the eusocial naked mole-rat, Heterocephalus glaber: a case of degenerative orthogenesis in the absence of sperm competition?社会性裸鼹鼠（Heterocephalus glaber）的精子结构和运动能力：在没有精子竞争的情况下退化性正构的案例？
BMC Evol Biol. 2011 Dec 5;11:351. doi: 10.1186/1471-2148-11-351.
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The naked mole rat--a new record for the oldest living rodent.裸鼹鼠——现存最古老啮齿动物的新纪录。
Sci Aging Knowledge Environ. 2002 May 29;2002(21):pe7. doi: 10.1126/sageke.2002.21.pe7.
9
Eusociality in a mammal: cooperative breeding in naked mole-rat colonies.一种哺乳动物的真社会性：裸鼹鼠群体中的合作繁殖。
Science. 1981 May 1;212(4494):571-3. doi: 10.1126/science.7209555.