裸鼹鼠的卵巢允许在单个样本中研究卵巢储备、体外生殖细胞扩增和卵母细胞体外成熟。
Naked mole rat ovaries allow investigation of ovarian reserve, in vitro germ cell expansion, and oocyte in vitro maturation within a single sample.
机构信息
Magee-Womens Research Institute, Department of Obstetrics, Gynecology & Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada.
出版信息
Reproduction. 2024 Apr 17;167(5). doi: 10.1530/REP-23-0459. Print 2024 May 1.
Abstract
Recently, we described that in the naked mole rat ovary it is possible to study the ovarian reserve and the mitotic expansion of the germ cell postnatally. Herein, we show oocyte in vitro maturation and in vitro germ cell expansion using the same ovary.
摘要
最近，我们描述了在裸鼹鼠的卵巢中，可以研究出生后卵巢储备和生殖细胞的有丝分裂扩增。在这里，我们使用相同的卵巢展示了卵母细胞的体外成熟和体外生殖细胞扩增。
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