一项关于石棉相关疾病剂量-反应关系的研究。
A study of dose-response relationships for asbestos associated disease.
作者信息
Finkelstein M M
出版信息
Br J Ind Med. 1985 May;42(5):319-25. doi: 10.1136/oem.42.5.319.
Abstract
The risk of an asbestos worker developing small irregular opacities on the chest radiograph is related to cumulative exposure to asbestos dust, latency, and smoking habit. In this study the use of residence-time weighted exposure as a "dose metric" was explored in a cohort of asbestos cement workers. It was found that this parameter, which incorporates both exposure concentration and latency, is useful for modelling the risk of small opacities and might also be useful for modelling the risk of mesothelioma.
摘要
石棉工人在胸部X光片上出现小的不规则阴影的风险与石棉粉尘的累积暴露、潜伏期和吸烟习惯有关。在本研究中，对一组石棉水泥工人探讨了使用居住时间加权暴露作为“剂量指标”。结果发现，这个综合了暴露浓度和潜伏期的参数，对于模拟小阴影的风险是有用的，并且可能对于模拟间皮瘤的风险也有用。
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本文引用的文献
1
Asbestosis in long-term employees of an Ontario asbestos-cement factory.
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2
Mesothelioma mortality in asbestos workers: implications for models of carcinogenesis and risk assessment.石棉工人的间皮瘤死亡率：对致癌作用模型和风险评估的影响。
Br J Cancer. 1982 Jan;45(1):124-35. doi: 10.1038/bjc.1982.15.
3
Radiographic abnormalities among asbestos-cement workers. An exposure-response study.
Am Rev Respir Dis. 1984 Jan;129(1):17-22. doi: 10.1164/arrd.1984.129.1.17.
4
Late progression of radiographic changes in Canari chrysotile mine and mill exworkers.
Arch Environ Health. 1983 Jan-Feb;38(1):54-8. doi: 10.1080/00039896.1983.10543979.
5
Radiological changes and fibre exposure in chrysotile workers aged 60-69 years at Thetford Mines.
Ann Occup Hyg. 1982;26(1-4):889-98.
6
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Arch Environ Health. 1974 Dec;29(6):338-40. doi: 10.1080/00039896.1974.10666611.
7
Trend and homogeneity analyses of proportions and life table data.比例及生命表数据的趋势与同质性分析。
Comput Biomed Res. 1977 Aug;10(4):373-81. doi: 10.1016/0010-4809(77)90006-4.
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