由拟茎点霉属引起的角膜炎经伏立康唑成功治疗：来自阿萨姆邦的病例系列。

Keratitis due to Lasiodiplodia theobromae successfully treated with voriconazole: A case series from Assam.

机构信息

ICMR Advanced Mycology Diagnostic and Research Center, Department of Microbiology, Assam Medical College and Hospital, Dibrugarh, Assam, India.

Department of Ophthalmology, Assam Medical College and Hospital, Dibrugarh, Assam, India.

出版信息

Indian J Med Microbiol. 2024 Mar-Apr;48:100558. doi: 10.1016/j.ijmmb.2024.100558. Epub 2024 Mar 16.

DOI:10.1016/j.ijmmb.2024.100558

PMID:38458337

Abstract

Lasiodiplodia theobromae is a dematiaceous fungus which rarely causes keratitis and is mostly resistant to the commonly used antifungal drugs. Here, we report three cases of keratitis caused by L.theobromae from Assam. All the cases were successfully treated with 1% voriconazole and surgical debridement. To the best of our knowledge and literature search, this is the first case series of keratitis caused by L.theobromae reported from eastern India.

摘要

热带假丝酵母是一种暗色真菌，很少引起角膜炎，且对常用抗真菌药物大多具有耐药性。在此，我们报告了来自阿萨姆邦的三例热带假丝酵母角膜炎病例。所有病例均通过 1%伏立康唑联合手术清创成功治愈。据我们所知和文献检索，这是首次在印度东部报告的由热带假丝酵母引起的角膜炎病例系列。