Suppr超能文献

急性主动脉闭塞:面向急诊临床医生的叙述性综述

Acute aortic occlusion: A narrative review for emergency clinicians.

作者信息

Pelletier Jessica, Koyfman Alex, Long Brit

机构信息

Department of Emergency Medicine, Washington University School of Medicine, St. Louis, MO, USA.

Department of Emergency Medicine, UT Southwestern, Dallas, TX, USA.

出版信息

Am J Emerg Med. 2024 May;79:192-197. doi: 10.1016/j.ajem.2024.02.033. Epub 2024 Feb 24.

Abstract

INTRODUCTION

Acute aortic occlusion (AAO) is a rare but serious condition associated with significant morbidity and mortality.

OBJECTIVE

This review provides an emergency medicine focused evaluation of AAO, including presentation, assessment, and emergency department (ED) management based on current evidence.

DISCUSSION

AAO refers to obstruction of blood flow through the aorta due to either thrombosis or embolism. This condition primarily affects older adults ages 60-70 with cardiovascular comorbidities and most commonly presents with signs and symptoms of acute limb ischemia, though the gastrointestinal tract, kidneys, and spinal cord may be affected. The first line imaging modality includes computed tomography angiography of the chest, abdomen, and pelvis. ED resuscitative management consists of avoiding extremes of blood pressure or heart rate, maintaining normal oxygen saturation and euvolemic status, anticoagulation with heparin, and pain control. Emergent consultation with the vascular surgery specialist is recommended to establish a plan for restoration of perfusion to ischemic tissues via endovascular or open techniques. High rates of baseline comorbidities present in the affected population as well as ischemic and reperfusion injuries place AAO patients at high risk for complications in an immediate and delayed fashion after surgical management.

CONCLUSIONS

An understanding of AAO can assist emergency clinicians in diagnosing and managing this rare but devastating disease.

摘要

引言

急性主动脉闭塞(AAO)是一种罕见但严重的疾病,具有较高的发病率和死亡率。

目的

本综述基于当前证据,对AAO进行以急诊医学为重点的评估,包括临床表现、评估以及急诊科(ED)管理。

讨论

AAO指由于血栓形成或栓塞导致主动脉血流阻塞。这种疾病主要影响60至70岁患有心血管合并症的老年人,最常见的表现是急性肢体缺血的体征和症状,不过胃肠道、肾脏和脊髓也可能受到影响。一线影像学检查方法包括胸部、腹部和骨盆的计算机断层血管造影。急诊科复苏管理包括避免血压或心率出现极端情况、维持正常的血氧饱和度和血容量正常状态、使用肝素进行抗凝以及控制疼痛。建议紧急咨询血管外科专家,以制定通过血管内或开放技术恢复缺血组织灌注的计划。受影响人群中存在的高比例基线合并症以及缺血和再灌注损伤,使AAO患者在手术治疗后立即和延迟发生并发症的风险很高。

结论

对AAO的了解有助于急诊临床医生诊断和管理这种罕见但具有破坏性的疾病。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验