Institute of Computer Science and Engineering, National Yang Ming Chiao Tung University, Hsinchu, Taiwan.
Institute of Statistics, National Yang Ming Chiao Tung University, Hsinchu, Taiwan; Department of Statistics and Data Science, Cornell University, Ithaca, New York, USA.
Artif Intell Med. 2024 Mar;149:102809. doi: 10.1016/j.artmed.2024.102809. Epub 2024 Feb 9.
Cardiovascular diseases, particularly arrhythmias, remain a leading cause of mortality worldwide. Electrocardiogram (ECG) analysis plays a pivotal role in cardiovascular disease diagnosis. Although previous studies have focused on waveform analysis and model training, integrating additional clinical information, especially demographic data, remains challenging. In this study, we present an innovative approach to ECG classification by incorporating demographic information from patients' medical histories through a colorization technique. Our proposed method maps demographic features onto the (R, G, B) color space through normalized scaling. Each demographic feature corresponds to a distinct color, allowing for different ECG leads to be colored. This approach preserves the relationships between data by maintaining the color correlations in the statistical features, enhancing ECG analytics and supporting precision medicine. We conducted experiments with PTB-XL dataset and achieved 1%-6% improvements in the area under the receiving operator characteristic curve performance compared with other methods for various classification problems. Notably, our method excelled in multiclass and challenging classification tasks. The combined use of color features and the original waveform shape features enhanced prediction accuracy for various deep learning models. Our findings suggest that colorization is a promising avenue for advancing ECG classification and diagnosis, contributing to improved prediction and diagnosis of cardiovascular diseases and ultimately enhancing clinical outcomes.
心血管疾病,尤其是心律失常,仍然是全球范围内导致死亡的主要原因。心电图(ECG)分析在心血管疾病诊断中起着关键作用。尽管之前的研究集中在波形分析和模型训练上,但整合额外的临床信息,特别是人口统计学数据,仍然具有挑战性。在这项研究中,我们通过一种颜色化技术,提出了一种通过整合患者病史中的人口统计学信息来进行心电图分类的创新方法。我们的方法通过归一化缩放将人口统计学特征映射到(R、G、B)颜色空间。每个人口统计学特征对应一种独特的颜色,允许不同的心电图导联被着色。这种方法通过保持统计特征中的颜色相关性来保留数据之间的关系,从而增强了心电图分析并支持精准医疗。我们在 PTB-XL 数据集上进行了实验,与其他方法相比,在各种分类问题上,我们的方法在接收者操作特征曲线性能的面积上提高了 1%-6%。值得注意的是,我们的方法在多类和具有挑战性的分类任务中表现出色。颜色特征和原始波形形状特征的结合使用提高了各种深度学习模型的预测准确性。我们的研究结果表明,颜色化是推进心电图分类和诊断的一个有前途的途径,有助于改善心血管疾病的预测和诊断,并最终提高临床结果。