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挑战与胜利:通过手术和药物干预成功治疗的骰骨结核不寻常表现

Challenges and Triumphs: Unusual Presentation of Tuberculosis in the Cuboid Bone Successfully Managed Through Surgical and Medical Intervention.

作者信息

Patel Hardik, Shrivastava Sandeep, Pundkar Aditya, Jaiswal Ankit M, Goyal Saksham

机构信息

Department of Orthopaedics, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research (Deemed to be University), Wardha, IND.

出版信息

Cureus. 2024 Feb 7;16(2):e53796. doi: 10.7759/cureus.53796. eCollection 2024 Feb.

DOI:10.7759/cureus.53796
PMID:38465128
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10923731/
Abstract

This case report describes the unusual presentation of tuberculosis (TB) affecting the cuboid bone in a 16-year-old male patient. The patient presented with a one-year history of progressive foot pain, a discharging sinus, evening rise of temperature, weight loss, and loss of appetite. Clinical examination revealed soft tissue swelling and the presence of caseous material oozing from the sinus. Emergency debridement and curettage were performed, and bone cementing was carried out. An intraoperative sample was sent for a culture sensitivity test, histological analysis, and cartridge-based nucleic acid amplification test (CBNAAT). Histopathological examination, CBNAAT, and culture and sensitivity tests confirmed the diagnosis of infection. Post-operatively, anti-tuberculous treatment was started. The patient fully recovered from TB of the cuboid.

摘要

本病例报告描述了一名16岁男性患者患有的累及骰骨的不寻常结核病表现。患者有一年渐进性足部疼痛、窦道流脓、体温傍晚升高、体重减轻和食欲不振的病史。临床检查发现软组织肿胀,窦道有干酪样物质渗出。进行了急诊清创和刮除术,并实施了骨水泥填充。术中样本送去做培养药敏试验、组织学分析和基于盒式的核酸扩增试验(CBNAAT)。组织病理学检查、CBNAAT以及培养和药敏试验确诊为感染。术后开始抗结核治疗。患者的骰骨结核完全康复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a859/10923731/617007073b16/cureus-0016-00000053796-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a859/10923731/b063463c94a3/cureus-0016-00000053796-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a859/10923731/f418f3a82057/cureus-0016-00000053796-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a859/10923731/617007073b16/cureus-0016-00000053796-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a859/10923731/b063463c94a3/cureus-0016-00000053796-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a859/10923731/f418f3a82057/cureus-0016-00000053796-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a859/10923731/617007073b16/cureus-0016-00000053796-i03.jpg

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Osteoarthritis Cartilage. 2022 Sep;30(9):1278-1286. doi: 10.1016/j.joca.2022.05.011. Epub 2022 Jun 14.
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