Merino Moya Francisco de Borja, Lucena Garcia Silvia, García Torrecillas Juan Manuel
Hospital Universitario Torrecárdenas.
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An Sist Sanit Navar. 2024 Mar 11;47(1):e1057. doi: 10.23938/ASSN.1057.
The study aim was to analyze the relationship between functional thyroid pathology and the exposure to work shifts / night shifts, and describe the most prevalent thyroid disorders based on the type of shift.
Cross-sectional study performed in the emergency department of a hospital in Almeria (Spain). Relationships between thyroxine and thyrotropin levels (TSH) and work shifts, professional category and history of thyroid pathology were analyzed.
The study included 133 workers; 80.5% female, average age was 46.11 years (38 - 65), and 52% were part of the nursing staff; thyroid disorders were more frequent in female participants. Most participants (81.2%) had rotating shifts schedules and 11.3% night shifts (12.1% female and 7.7% male). Thyroid alterations were found in 27% of the participants (usually elevated TSH levels and normal thyroxine levels), particularly in those doing night shifts (61.1%). TSH alterations were more frequent in individuals doing night shifts than in rotating shifts (53.3 vs 13.0%; p<0.001). Individuals working night shifts had mean TSH values in the normal range, although significantly higher than the individuals in the rest of the shifts; thyroxine levels were found to be similar. No thyroid disorders were found in day shift participants. Night shift and a history of thyroid pathology were independent predictors of thyroid disorders.
Night shift schedules and history of thyroid disorders are more frequent in female, both related to the presence of thyroid disorders, indicating the need to include the evaluation of these disorders in health surveillance programs and analyze gender differences.
本研究旨在分析甲状腺功能病理学与轮班/夜班工作暴露之间的关系，并根据轮班类型描述最常见的甲状腺疾病。
在西班牙阿尔梅里亚一家医院的急诊科进行横断面研究。分析了甲状腺素和促甲状腺激素水平（TSH）与轮班工作、职业类别及甲状腺疾病史之间的关系。
该研究纳入了133名工作人员；女性占80.5%，平均年龄为46.11岁（38 - 65岁），52%为护理人员；甲状腺疾病在女性参与者中更为常见。大多数参与者（81.2%）有轮班时间表，11.3%有夜班（女性占12.1%，男性占7.7%）。27%的参与者存在甲状腺改变（通常TSH水平升高而甲状腺素水平正常），尤其是那些从事夜班工作的人（61.1%）。从事夜班工作的人TSH改变比轮班工作的人更频繁（53.3%对13.0%；p<0.001）。从事夜班工作的人的TSH平均水平在正常范围内，尽管明显高于其他班次的人；甲状腺素水平相似。日班参与者未发现甲状腺疾病。夜班工作和甲状腺疾病史是甲状腺疾病的独立预测因素。
夜班时间表和甲状腺疾病史在女性中更为常见，二者均与甲状腺疾病的存在有关，这表明有必要在健康监测项目中纳入对这些疾病的评估并分析性别差异。
