Suppr超能文献

哪些因素与早期影像学骨关节炎患者全髋关节置换术后的成功结果相关?

Which factors are associated with a successful outcome following total hip arthroplasty in patients with early radiographic osteoarthritis?

机构信息

Wrightington Lower Limb Unit, Wrightington Centre for Hip Surgery, Wrightington Hospital, Wigan, England, UK.

出版信息

Hip Int. 2024 Sep;34(5):588-595. doi: 10.1177/11207000241235892. Epub 2024 Mar 11.

Abstract

BACKGROUND

It is unclear which factors are associated with a successful total hip arthroplasty (THA) in patients with early radiographic osteoarthritis (OA).

METHODS

70 patients with early OA (Kellgren and Lawrence [KL] grades 0-2) who underwent THA were compared with 200 patients with advanced OA (KL grades 3-4). Outcomes were Oxford Hip Scores (OHS), EQ-5D and EQ-VAS scores; compared preoperatively with 1 year postoperatively. We investigated which clinical and radiographic (plain x-ray, CT, MRI) features predicted successful THA (postoperative OHS ⩾42).

RESULTS

The early OA group were significantly younger (61 vs. 66 years; [  0.0035). There were no significant differences in BMI, ASA grade or gender. After adjusting for confounders, the advanced OA group had a significantly greater percentage of possible change (PoPC) in OHS (75.8% vs. 50.4%;   0.0001) and improvement in EQ-5D (0.151 vs. 0.002;   0.0001). There were no significant differences in complication, revision or readmission rates. In the early OA group, 16/70 (22.9%) patients had a 'successful' THA. Patients who had a 'successful' THA were significantly more likely to have subchondral cysts on CT/MRI (91.7% vs. 57.7%;   0.0362). The presence of cysts on CT/MRI was associated with a significantly greater PoPC in OHS (61.6% vs. 38.2%;   0.0353). The combination of cysts and joint space width <1 mm was associated with a PoPC of 68%.

CONCLUSIONS

THA in patients with early OA (KL grades 0-2) on plain radiographs should be indicated with caution. We advocate preoperative cross-sectional imaging in these patients. In the absence of cysts on CT/MRI, a THA seems unlikely to provide a satisfactory outcome.

摘要

背景

目前尚不清楚哪些因素与早期影像学骨关节炎(OA)患者的全髋关节置换术(THA)成功相关。

方法

将 70 例早期 OA(Kellgren 和 Lawrence [KL] 分级 0-2)患者与 200 例晚期 OA(KL 分级 3-4)患者进行比较。术后 1 年进行牛津髋关节评分(OHS)、EQ-5D 和 EQ-VAS 评分比较。我们研究了哪些临床和影像学(普通 X 线、CT、MRI)特征可预测 THA 成功(术后 OHS ⩾42)。

结果

早期 OA 组明显更年轻(61 岁比 66 岁;P<0.0035)。两组 BMI、ASA 分级或性别无显著差异。调整混杂因素后,晚期 OA 组 OHS 的可能变化百分比(PoPC)显著更大(75.8%比 50.4%;P<0.0001),EQ-5D 改善程度也更大(0.151 比 0.002;P<0.0001)。并发症、翻修或再入院率无显著差异。在早期 OA 组中,70 例患者中有 16 例(22.9%)THA 成功。THA 成功的患者 CT/MRI 上更有可能存在软骨下囊肿(91.7%比 57.7%;P<0.0362)。CT/MRI 上存在囊肿与 OHS 的 PoPC 显著更大相关(61.6%比 38.2%;P<0.0353)。囊肿与关节间隙宽度 <1mm 的联合存在与 PoPC 为 68%相关。

结论

对于普通 X 线片显示早期 OA(KL 分级 0-2)的患者,THA 的应用应谨慎。我们提倡对这些患者进行术前横断面成像。如果 CT/MRI 上没有囊肿,THA 似乎不太可能获得满意的结果。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验