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Assessment of antiprotease activity of some carbamate derivatives.

作者信息

Shinogi M, Agha B J, Tsuji K, Digenis G A

出版信息

J Pharm Sci. 1985 Apr;74(4):482-5. doi: 10.1002/jps.2600740424.

DOI:10.1002/jps.2600740424
PMID:3846631
Abstract

Six carbamate derivatives were tested for inhibitory activity towards porcine pancreatic elastase, trypsin, and chymotrypsin. Only three esters that are isatoic anhydride derivatives were found to inhibit elastase competitively but nonspecifically. KI values for the best two inhibitors were determined from Dixon plots.

摘要

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