Liu Lu, Deng Xiao-Qiang, Zhao Yong-Jie, Ma Rong-Xing, Yang Li, Song Kun-Xiu, Zhang Jing-Yu, Hu Yong-Cheng
Graduate School, Tianjin Medical University, 22 Qixiangtai Road, Tianjin, China.
Xing'anmeng People's Hospital, 66 Hanshan West Street, Ulanhot, Inner Mongolia, China.
Sci Rep. 2024 Mar 11;14(1):5867. doi: 10.1038/s41598-024-56645-7.
To illustrate the surgical technique and explore clinical outcomes of the reconstruction for the malignant and metastatic bone tumour of proximal femur with metallic modular intercalary prosthesis. Sixteen patients who underwent modular intercalary prosthetic reconstruction after tumour resection were included from April 2012 and October 2020. Prosthesis and screws parameters, resected bone length and residual bone length, clinical outcomes and survivorship were analyzed. All patients were followed up for an average of 19 months (range 1-74). In our series, 12 patients died of the progression of the primary disease at the final follow-up. The cumulative survivorship since the treatment of proximal femoral metastasis was 78.6% (11 patients) at 6 months and 38.5% (5 patients) at 1 year. The mean MSTS score was 22.25 ± 4.55 among all patients. There were no cases of loosening or breakage of the prostheses, plates or screws, despite the various measurements of prostheses and residual bones. Modular intercalary prosthetic reconstruction was an effective method for malignant tumour of the proximal femur, including the advantages of providing early pain relief, quickly restoring postoperative function, required a short operation time, and preserving the adjacent joints.
为阐述采用金属模块化插入式假体对股骨近端恶性和转移性骨肿瘤进行重建的手术技术并探索临床疗效。纳入2012年4月至2020年10月期间16例肿瘤切除后接受模块化插入式假体重建的患者。分析假体及螺钉参数、切除骨长度和残留骨长度、临床疗效及生存率。所有患者平均随访19个月(范围1 - 74个月)。在我们的系列研究中,12例患者在末次随访时死于原发疾病进展。自股骨近端转移治疗后的累积生存率在6个月时为78.6%(11例患者),1年时为38.5%(5例患者)。所有患者的平均肌肉骨骼肿瘤学会(MSTS)评分为22.25±4.55。尽管假体和残留骨有各种测量数据,但未出现假体、钢板或螺钉松动或断裂的情况。模块化插入式假体重建是治疗股骨近端恶性肿瘤的有效方法,具有能早期缓解疼痛、快速恢复术后功能、手术时间短以及保留相邻关节等优点。