Van-Londoño Isabella, Ramírez-Giraldo Camilo, Martínez Echeverri Julio César, Villany-Sarmiento Juan José, Fino-Velásquez Laura Marcela
Universidad del Rosario, Bogotá, Colombia.
Hospital Universitario Mayor - Méderi, Bogotá, Colombia.
Heliyon. 2024 Mar 2;10(5):e26885. doi: 10.1016/j.heliyon.2024.e26885. eCollection 2024 Mar 15.
Eosinophilic gastroenteritis (EGE) is a rare disease which mainly consists of an abnormal eosinophile infiltration of the gastrointestinal tract. It's classified according to its location: eosinophilic esophagitis, eosinophilic gastritis, eosinophilic enteritis (including duodenum, jejunum and/or ileum) and eosinophilic colitis and degree of infiltration (mucosal, muscular, serosal). Depending on eosinophile concentration, type of EGE and the patient's condition it may manifest with different clinical presentations such as functional dyspepsia, abdominal pain, irritability, hypoproteinemia, diarrhea, anemia, among others. Few research has been done on such an uncommon pathology to the extent that treatment evidence is mostly limited to small case series. This case study reports an infrequent presentation of EGE in the small and large intestine as an undifferentiated gastrointestinal disease and successful corticoid management given to the patient in order to further broaden knowledge on this subject and facilitate an established clinical conduct for the treating physician.
嗜酸性粒细胞性胃肠炎（EGE）是一种罕见疾病，主要表现为胃肠道嗜酸性粒细胞异常浸润。它根据浸润部位分类：嗜酸性粒细胞性食管炎、嗜酸性粒细胞性胃炎、嗜酸性粒细胞性肠炎（包括十二指肠、空肠和/或回肠）以及嗜酸性粒细胞性结肠炎，还根据浸润程度（黏膜、肌层、浆膜）分类。根据嗜酸性粒细胞浓度、EGE类型和患者病情，其临床表现可能不同，如功能性消化不良、腹痛、易怒、低蛋白血症、腹泻、贫血等。针对这种罕见病理的研究很少，以至于治疗证据大多限于小病例系列。本病例研究报告了一例罕见的EGE表现为未分化的胃肠道疾病，累及小肠和大肠，并对患者成功进行了皮质类固醇治疗，以进一步拓宽对该主题的认识，并为治疗医生确立临床行为提供便利。
