Kuri K, Lee M
Department of Internal Medicine, University of Texas Health Science Center, San Antonio 78284-7878.
South Med J. 1994 Sep;87(9):956-7. doi: 10.1097/00007611-199409000-00021.
Eosinophilic gastroenteritis (EGE) is a rare condition of unknown cause characterized by peripheral eosinophilia, eosinophilic infiltration of the gastrointestinal tract, and gastrointestinal symptomatology. EGE is generally classified according to the layer of gastrointestinal tract involved. Mucosal involvement, the most common form of presentation, may result in abdominal pain, nausea, vomiting, diarrhea, anemia, and protein-losing enteropathy. Patients with muscular layer disease generally have gastrointestinal obstruction. Serosal eosinophilic infiltration, the rarest form of presentation, may result in development of eosinophilic ascites. EGE complicated by ascites can be effectively treated with steroids after other systemic disorders associated with peripheral eosinophilia have been ruled out.
嗜酸性粒细胞性胃肠炎(EGE)是一种病因不明的罕见疾病,其特征为外周嗜酸性粒细胞增多、胃肠道嗜酸性粒细胞浸润以及胃肠道症状。EGE通常根据胃肠道受累的层次进行分类。黏膜受累是最常见的表现形式,可能导致腹痛、恶心、呕吐、腹泻、贫血和蛋白丢失性肠病。肌肉层疾病患者通常会出现胃肠道梗阻。浆膜嗜酸性粒细胞浸润是最罕见的表现形式,可能导致嗜酸性腹水的形成。在排除与外周嗜酸性粒细胞增多相关的其他全身性疾病后,EGE合并腹水可通过类固醇有效治疗。