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Comment on Manzoor, H. et al. Efficacy of Different Dosing Regimens of IgE Targeted Biologic Omalizumab for Chronic Spontaneous Urticaria in Adult and Pediatric Populations: A Meta-Analysis. 2022, , 2579.评论：曼佐尔，H.等人。成人和儿童慢性自发性荨麻疹中不同剂量方案的IgE靶向生物制剂奥马珠单抗的疗效：一项荟萃分析。2022年，，2579。
Healthcare (Basel). 2024 Feb 28;12(5):553. doi: 10.3390/healthcare12050553.
2
Efficacy of Different Dosing Regimens of IgE Targeted Biologic Omalizumab for Chronic Spontaneous Urticaria in Adult and Pediatric Populations: A Meta-Analysis.IgE靶向生物制剂奥马珠单抗不同给药方案对成人和儿童慢性自发性荨麻疹的疗效：一项荟萃分析
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Update on Omalizumab for Urticaria: What's New in the Literature from Mechanisms to Clinic.荨麻疹奥马珠单抗治疗的最新进展：从发病机制到临床应用的文献综述。
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Efficacy and safety of omalizumab in patients with chronic urticaria who exhibit IgE against thyroperoxidase.奥马珠单抗治疗针对甲状腺过氧化物酶的 IgE 的慢性荨麻疹患者的疗效和安全性。
J Allergy Clin Immunol. 2011 Jul;128(1):202-209.e5. doi: 10.1016/j.jaci.2011.04.038. Epub 2011 Jun 2.
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Clinical efficacy of omalizumab in chronic spontaneous urticaria is associated with a reduction of FcεRI-positive cells in the skin.奥马珠单抗治疗慢性自发性荨麻疹的临床疗效与皮肤中FcεRI阳性细胞数量减少有关。
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Anti-TPO IgG/Total IgE Ratio: Biomarker for Omalizumab Response Prediction in Chronic Spontaneous Urticaria.抗甲状腺过氧化物酶 IgG/总 IgE 比值：预测奥马珠单抗治疗慢性自发性荨麻疹反应的生物标志物。
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Efficacy of Omalizumab in Patients with Chronic Spontaneous Urticaria and Its Association with Serum IgE Levels and Eosinophil Count.奥马珠单抗治疗慢性自发性荨麻疹的疗效及其与血清IgE水平和嗜酸性粒细胞计数的关系。
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The clinical response to omalizumab in chronic spontaneous urticaria patients is linked to and predicted by IgE levels and their change.奥马珠单抗治疗慢性自发性荨麻疹患者的临床应答与 IgE 水平及其变化相关，并可预测。
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本文引用的文献

1
Efficacy of Different Dosing Regimens of IgE Targeted Biologic Omalizumab for Chronic Spontaneous Urticaria in Adult and Pediatric Populations: A Meta-Analysis.IgE靶向生物制剂奥马珠单抗不同给药方案对成人和儿童慢性自发性荨麻疹的疗效：一项荟萃分析
Healthcare (Basel). 2022 Dec 19;10(12):2579. doi: 10.3390/healthcare10122579.
2
Adjunct therapy with probiotics for chronic urticaria in children: randomised placebo-controlled trial.益生菌辅助治疗儿童慢性荨麻疹：随机安慰剂对照试验。
Allergy Asthma Clin Immunol. 2021 Apr 17;17(1):39. doi: 10.1186/s13223-021-00544-3.
3
Omalizumab rapidly improves angioedema-related quality of life in adult patients with chronic spontaneous urticaria: X-ACT study data.奥马珠单抗可显著改善慢性自发性荨麻疹成年患者血管性水肿相关生活质量：X-ACT 研究数据。
Allergy. 2018 Mar;73(3):576-584. doi: 10.1111/all.13339. Epub 2017 Dec 11.
4
Omalizumab efficacy in cases of chronic spontaneous urticaria is not explained by the inhibition of sera activity in effector cells.奥马珠单抗治疗慢性自发性荨麻疹的疗效不能用抑制效应细胞中血清活性来解释。
Sci Rep. 2017 Aug 21;7(1):8985. doi: 10.1038/s41598-017-09361-4.
5
Effect of omalizumab on angioedema in H1 -antihistamine-resistant chronic spontaneous urticaria patients: results from X-ACT, a randomized controlled trial.奥马珠单抗对 H1 抗组胺药耐药性慢性自发性荨麻疹患者血管性水肿的影响：X-ACT 随机对照试验的结果。
Allergy. 2016 Aug;71(8):1135-44. doi: 10.1111/all.12870. Epub 2016 Mar 31.
6
Omalizumab in patients with symptomatic chronic idiopathic/spontaneous urticaria despite standard combination therapy.奥马珠单抗治疗标准联合治疗后仍有症状的慢性特发性/自发性荨麻疹患者。
J Allergy Clin Immunol. 2013 Jul;132(1):101-9. doi: 10.1016/j.jaci.2013.05.013.
7
Efficacy and safety of omalizumab in patients with chronic urticaria who exhibit IgE against thyroperoxidase.奥马珠单抗治疗针对甲状腺过氧化物酶的 IgE 的慢性荨麻疹患者的疗效和安全性。
J Allergy Clin Immunol. 2011 Jul;128(1):202-209.e5. doi: 10.1016/j.jaci.2011.04.038. Epub 2011 Jun 2.

评论：曼佐尔，H.等人。成人和儿童慢性自发性荨麻疹中不同剂量方案的IgE靶向生物制剂奥马珠单抗的疗效：一项荟萃分析。2022年，，2579。

Comment on Manzoor, H. et al. Efficacy of Different Dosing Regimens of IgE Targeted Biologic Omalizumab for Chronic Spontaneous Urticaria in Adult and Pediatric Populations: A Meta-Analysis. 2022, , 2579.

作者信息

Tajerian Amin

机构信息

School of Medicine, Arak University of Medical Sciences, Arak 3819693345, Iran.

出版信息

Healthcare (Basel). 2024 Feb 28;12(5):553. doi: 10.3390/healthcare12050553.

DOI:10.3390/healthcare12050553
PMID:38470665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10931475/
Abstract

In December 2022, the paper "Efficacy of Different Dosing Regimens of IgE Targeted Biologic Omalizumab for Chronic Spontaneous Urticaria in Adult and Pediatric Populations: A Meta-Analysis" was published in the journal [...].

摘要

2022年12月，论文《成人和儿童人群中IgE靶向生物制剂奥马珠单抗不同给药方案治疗慢性自发性荨麻疹的疗效：一项荟萃分析》发表于期刊[...]。