Chaudhry Maaria, Botterbush Kathleen, Zhang Justin K, Coppens Jeroen
Department of Neurosurgery, Saint Louis University Hospital, St. Louis, Missouri, USA
Department of Neurosurgery, Saint Louis University Hospital, St. Louis, Missouri, USA.
BMJ Case Rep. 2024 Mar 12;17(3):e258534. doi: 10.1136/bcr-2023-258534.
There is no standard of care for management of Rathke cleft cysts (RCCs), and protocol for spontaneous rupture or residual capsule fragments is not well documented.Our case involves a Caucasian man in his 80s who presented with muscle weakness, fatigue, bitemporal hemianopia and pain. Further examination demonstrated decreased thyroid and cortisol levels. MRI revealed a 1.6×1.5×1.3 cm sellar homogenous mass with extension into the suprasellar cistern. While the size of the cyst was rather large, a decision was made to follow conservatively with serial MRI. At 3 years, the mass had spontaneously regressed. The patient was asymptomatic without imaging evidence of RCC recurrence at 4-year follow-up.Classic indications for surgical intervention in suprasellar cysts were subtle in our patient and his advanced age made us take a conservative approach. Current data are lacking regarding management of RCCs presenting with endocrine dysfunction. Our case suggests that RCCs presenting with endocrine dysfunction may be managed conservatively with serial imaging-based monitoring.
对于拉克氏裂囊肿(RCCs)的管理,目前尚无标准的治疗方案,关于其自发破裂或残留囊壁碎片的处理方案也缺乏充分的文献记载。我们的病例是一位80多岁的白人男性,他出现了肌肉无力、疲劳、双颞侧偏盲和疼痛症状。进一步检查显示甲状腺和皮质醇水平降低。MRI检查发现鞍区有一个1.6×1.5×1.3厘米的均匀肿块,并延伸至鞍上池。尽管囊肿尺寸较大,但还是决定采用连续MRI检查进行保守观察。3年后,肿块自行消退。在4年的随访中,患者无症状,且没有RCC复发的影像学证据。在我们的患者中,鞍上囊肿手术干预的典型指征并不明确,而且他的高龄促使我们采取保守的治疗方法。目前缺乏关于伴有内分泌功能障碍的RCCs管理的相关数据。我们的病例表明,对于伴有内分泌功能障碍的RCCs,可通过基于影像学的连续监测进行保守治疗。