Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200, 00128, Roma, Italy.
Department of Ophthalmology, University of British Columbia, Vancouver, Canada.
Aesthetic Plast Surg. 2024 Aug;48(16):3154-3162. doi: 10.1007/s00266-024-03921-6. Epub 2024 Mar 12.
Since aesthetic medical treatments providing natural results are becoming increasingly popular, we developed an innovative hyaluronic acid infiltration technique for midface rejuvenation.
In this prospective study, only patients with a negative or neutral lower eyelid vector were included. Treatment consisted in injecting three hyaluronic acid boluses at the cutaneous projections of the levator labii superioris, zygomatic major and minor muscles insertions. All patients were administered before treatment the FACE-Q questionnaire, whereas after treatment, they were administered the FACE-Q questionnaire and the Global Aesthetic Improvement Scale (GAIS). All treatments were documented with standardized photographs. A plastic surgeon from another Institution reviewed the photos and scored the treatments according to the GAIS scale.
We included 567 patients (101 males and 466 females) who met the inclusion criteria. The mean age was 41 years, and mean follow-up time was four months. The FACE-Q scores after treatment were significantly higher (p < 0.001) in every domain investigated. The GAIS scores demonstrated significant improvement posttreatment in 89.8% of patients. An average of 1.5 ml of hyaluronic acid (VYC-20) was used for each zygomatic region. No major complications were reported; only 27 patients reported bruising, which resolved spontaneously. In all patients, there was an inversion of the lower eyelid vector, which had transitioned from neutral or negative to positive.
Lifting the insertions of three selected muscles with hyaluronic acid allows a midface upward repositioning. This technique provides a reproducible and safe approach for midface rejuvenation through tissue repositioning rather than augmenting facial volume.
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由于提供自然效果的美容医学治疗越来越受欢迎，我们开发了一种用于中面部年轻化的新型透明质酸渗透技术。
在这项前瞻性研究中，仅纳入下眼睑向量为阴性或中性的患者。治疗包括在提上唇肌、颧大肌和颧小肌附着处的皮肤投影处注射三个透明质酸团块。所有患者在治疗前均接受 FACE-Q 问卷评估，治疗后接受 FACE-Q 问卷和全球美学改善量表（GAIS）评估。所有治疗均通过标准化照片记录。另一家机构的整形外科医生查看照片，并根据 GAIS 量表对治疗进行评分。
我们纳入了 567 名符合纳入标准的患者（101 名男性和 466 名女性）。平均年龄为 41 岁，平均随访时间为四个月。治疗后每个调查领域的 FACE-Q 评分均显著升高（p<0.001）。89.8%的患者 GAIS 评分治疗后显著改善。每个颧骨区域平均使用 1.5 毫升透明质酸（VYC-20）。未报告重大并发症；仅 27 例患者报告出现瘀伤，可自行消退。在所有患者中，下眼睑向量均发生反转，从中性或阴性变为阳性。
用透明质酸提升三个选定肌肉的附着点可使中面部向上重新定位。这种技术通过组织重新定位而不是增加面部体积，为中面部年轻化提供了一种可重复且安全的方法。
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