Department of Marine Biotechnology, Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Ensenada, Mexico.
Curr Microbiol. 2024 Mar 12;81(5):110. doi: 10.1007/s00284-024-03636-6.
Some species of Dunaliella produce high levels of β-carotene, which is the largest natural Vitamin A source. β-carotene production in Dunaliella is expensive due to low yields obtained under culture conditions used. Since three decades ago synthetic β-carotene has dominated 98% of world market, even when synthetic is less bioactive than Dunaliella β-carotene molecule. In vitro experiments have been performed to increase β-carotene productivity in Dunaliella and some useful results have been obtained. In this review, culture conditions used in those experiments were compared to identify parameters that improved β-carotene productivity in Dunaliella. Comparison results show that β-carotene in vitro production can be increased regulating some specific culture conditions.
有些杜氏盐藻品种能产生大量的β-胡萝卜素,它是最大的天然维生素 A 来源。由于在培养条件下产量较低,杜氏盐藻中β-胡萝卜素的生产非常昂贵。自三十年前以来,合成β-胡萝卜素已占据了全球 98%的市场,尽管其生物活性不如杜氏盐藻β-胡萝卜素分子高。人们已经进行了体外实验来提高杜氏盐藻中的β-胡萝卜素产量,并取得了一些有用的结果。在本综述中,对这些实验中使用的培养条件进行了比较,以确定能提高杜氏盐藻β-胡萝卜素产量的参数。比较结果表明,通过调节一些特定的培养条件可以提高体外β-胡萝卜素的产量。