Zhang Jin, Chen Xingyi, Han Lu, Ma Biao, Tian Mengting, Bai Changcai, Zhang Ye
College of Pharmacy, Ningxia Medical University, Yinchuan 750004, China.
Key Laboratory of Ningxia Ethnomedicine Modernization, Ministry of Education, Ningxia Medical University, Yinchuan 750004, China.
Molecules. 2024 Feb 21;29(5):941. doi: 10.3390/molecules29050941.
Rupr. (CSR) belongs to the family . It is a perennial succulent parasitic herb with a reddish-brown coloration, predominantly submerged in sand and lacking chlorophyll. Traditionally, it has been used in ethnic medicine to treat various diseases, such as gastric ulcers, indigestion, bowel movements, and improving sexual function. To comprehensively collect CSR data, extensive literature searches were conducted using medical, ecological, and scientific databases such as Google Scholar, PubMed, Science Direct, Web of Science, and China National Knowledge Infrastructure (CNKI). This article summarizes and categorizes research on the uses, phytochemical characteristics, pharmacological activities, and toxicity of ethnic medicine, with the aim of establishing a solid foundation and proposing new avenues for exploring and developing potential applications of CSR. So far, a total of 98 compounds have been isolated and identified from CSR, including flavonoids, terpenes, steroids, and other compounds. It is worth noting that flavonoids and polysaccharides have significant antioxidant and anti-inflammatory properties. In addition, these compounds also show good application prospects in anti-tumor, antioxidant, anti-aging, anti-fatigue, anti-diabetes, and other aspects. Although extensive progress has been made in the basic research of CSR, further research is still needed to enhance the understanding of its mechanism of action and explore more unknown compounds. Our review indicates that CSR has broad prospects and deserves further research.
肉苁蓉（CSR）属于列当科。它是一种多年生肉质寄生草本植物，呈红棕色，主要埋于沙地中且缺乏叶绿素。传统上，它在民族医学中被用于治疗各种疾病，如胃溃疡、消化不良、促进肠道蠕动以及改善性功能。为了全面收集肉苁蓉的数据，我们使用了谷歌学术、PubMed、科学Direct、科学网和中国知网等医学、生态和科学数据库进行了广泛的文献检索。本文对民族医学中肉苁蓉的用途、植物化学特征、药理活性和毒性研究进行了总结和分类，旨在奠定坚实基础，并为探索和开发肉苁蓉的潜在应用提出新途径。到目前为止，已从肉苁蓉中分离并鉴定出总共98种化合物，包括黄酮类、萜类、甾体类和其他化合物。值得注意的是，黄酮类和多糖具有显著的抗氧化和抗炎特性。此外，这些化合物在抗肿瘤、抗氧化、抗衰老、抗疲劳、抗糖尿病等方面也显示出良好的应用前景。尽管肉苁蓉的基础研究已取得广泛进展，但仍需要进一步研究以加深对其作用机制的理解，并探索更多未知化合物。我们的综述表明，肉苁蓉具有广阔的前景，值得进一步研究。
