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Fadil Ilham, Ailal Fatima, Beziat Vivien, Casanova Jean Laurent, Boisson Bertrand, Bousfiha Ahmed Aziz

Laboratory of Clinical Immunology, Inflammation and Allergy (LICIA), Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.

Clinical Immunology Unit, Infectious Diseases Department, Children's Hospital, CHU Ibn Rochd, Casablanca, Morocco.

Tunis Med. 2023 Dec 5;101(12):862-870.

The detection of a high serum immunoglobulin E (IgE) level is first suggestive of allergy, atopy or parasitosis. However, some very high values can be a sign of more severe diseases. We propose a diagnostic strategy based on clinical and biological data to identify the various hereditary immune diseases that also present with abnormally high serum IgE levels.

血清免疫球蛋白E（IgE）水平升高首先提示过敏、特应性或寄生虫病。然而，一些极高的值可能是更严重疾病的迹象。我们提出一种基于临床和生物学数据的诊断策略，以识别同样表现为血清IgE水平异常升高的各种遗传性免疫疾病。