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腹腔镜胆囊切除术中意外发现孤立性肝结核:1 例报告。

Unexpected isolated hepatic tuberculosis discovered during laparoscopic cholecystectomy: A case report.

机构信息

Gastro-enterology department, Charles Nicolle University Hospital, Tunis, Tunisia.

Faculty of medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.

出版信息

Tunis Med. 2023 Dec 5;101(12):925-927.

Abstract

Isolated hepatic tuberculosis is a rare form of extrapulmonary tuberculosis. We report an exceptional case of a 51-year-old female patient complaining from right upper abdominal quadrant pain, who underwent laparoscopic surgery for millimetric gallbladder polyps. Preoperative ultrasound hepatic morphology and biochemical hepatic tests revealed no abnormalities. There were no clinical patterns for an active tuberculosis. During surgery time, scattered sub-centimeter whitish nodular lesions were discovered on the upper surface of the liver. Although gallbladder pathological examination did not reveal any significant abnormalities, per surgery hepatic biopsy indicated the presence of a giant cell granuloma with caseous necrosis highly suggestive of hepatic tuberculosis. Treatment by anti-bacillary drugs according to local standard protocol was conducted with favorable outcomes. Therefore, diagnosis of hepatic tuberculosis may be considered in endemic countries in totally asymptomatic patients or complaining from unexplained and isolated abdominal pain, in absence of any morphologic or biochemical hepatic abnormalities.

摘要

孤立性肝结核是一种罕见的肺外结核形式。我们报告了一例特殊的病例,一名 51 岁女性患者因右上腹疼痛就诊,因毫米大小的胆囊息肉而行腹腔镜手术。术前超声肝形态和生化肝检查均未见异常。没有活动性肺结核的临床特征。手术过程中,发现肝上表面有散在的亚厘米白色小结节状病变。尽管胆囊病理检查未见明显异常,但手术肝活检提示存在巨细胞肉芽肿伴干酪样坏死,高度提示肝结核。根据当地标准方案使用抗结核药物进行治疗,结果良好。因此,在无任何形态或生化肝异常的情况下,对于来自流行地区的完全无症状患者或因不明原因孤立性腹痛而就诊的患者,应考虑肝结核的诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4188/11261494/ffecbdeaa62c/capture1.jpg

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