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膀胱过度活动症会对勃起功能产生负面影响,并导致早泄:来自大型代表性人群水平研究的结果。

Overactive bladder negatively affects erectile function and promotes premature ejaculation: findings from large representative population-level study.

机构信息

Department of Urology, Jagiellonian University Medical College, Krakow, Poland.

Department of Urology, Royal Hallamshire Hospital, Sheffield, UK.

出版信息

World J Urol. 2024 Mar 13;42(1):139. doi: 10.1007/s00345-024-04841-5.

Abstract

PURPOSE

The effect of overactive bladder (OAB) on sexual health has been evaluated extensively for women but much less for men. Therefore, the aim of this study was to evaluate the relationship between OAB and men's sexual activity and the effect of OAB on erectile dysfunction (ED) and premature ejaculation (PE) in a large representative cohort of men at the population level.

METHODS

This study was based on computer-assisted web interviews that used validated questionnaires. The most recent census and the sample size estimation calculations were employed to produce a population-representative pool.

RESULTS

The study included 3001 men, representative of the population in terms of age and place of residence. The frequency of sexual intercourse was higher for respondents without OAB symptoms compared with persons who had OAB (p = 0.001), but there was no association between OAB symptoms and number of sexual partners (p = 0.754). Regression models did not confirm the effect of OAB on sexual activity (odds ratio 0.993, CI 0.974-1.013, p = 0.511). Both ED and PE were more prevalent in respondents with OAB symptoms compared with persons who lacked those symptoms (p < 0.001). Importantly, the effect of OAB on ED or PE was independent of age, comorbidities, and lifestyle habits (regression coefficients of 0.13 and 0.158 for ED and PE, respectively).

CONCLUSION

Overactive bladder did not significantly affect men's sexual activity, but it significantly correlated with ED and PE. Our results suggest a need in daily clinical practice to screen for OAB symptoms for persons who report ED or PE.

摘要

目的

过度膀胱活动症(OAB)对女性的性生活影响已得到广泛评估,但对男性的影响评估较少。因此,本研究的目的是评估 OAB 与男性性生活的关系,以及 OAB 对男性勃起功能障碍(ED)和早泄(PE)的影响,这是在人群水平上对大量具有代表性的男性队列进行的研究。

方法

本研究基于使用经过验证的问卷进行的计算机辅助网络访谈。最近的人口普查和样本量估计计算被用于产生一个具有代表性的人群样本。

结果

研究包括 3001 名男性,在年龄和居住地方面代表了人群。与患有 OAB 的人相比,没有 OAB 症状的受访者的性交频率更高(p=0.001),但 OAB 症状与性伴侣数量之间没有关联(p=0.754)。回归模型并未证实 OAB 对性生活的影响(优势比 0.993,CI 0.974-1.013,p=0.511)。与没有这些症状的人相比,有 OAB 症状的受访者中 ED 和 PE 的患病率更高(p<0.001)。重要的是,OAB 对 ED 或 PE 的影响独立于年龄、合并症和生活方式习惯(ED 和 PE 的回归系数分别为 0.13 和 0.158)。

结论

OAB 并未显著影响男性的性生活,但与 ED 和 PE 显著相关。我们的研究结果表明,在日常临床实践中,对于报告 ED 或 PE 的患者,有必要对 OAB 症状进行筛查。

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