School of Agriculture, Shenzhen Campus, Sun Yat-sen University, Guangdong, Shenzhen 518107, China.
School of Agriculture, Shenzhen Campus, Sun Yat-sen University, Guangdong, Shenzhen 518107, China; Key Laboratory for Quality Control of Characteristic Fruits and Vegetables of Hubei Province, College of Life Science and Technology, Hubei Engineering University, Xiaogan 432000, China.
Microbiol Res. 2024 Jun;283:127688. doi: 10.1016/j.micres.2024.127688. Epub 2024 Mar 8.
Plant secondary metabolites possess a wide range of pharmacological activities and play crucial biological roles. They serve as both a defense response during pathogen attack and a valuable drug resource. The role of microorganisms in the regulation of plant secondary metabolism has been widely recognized. The addition of specific microorganisms can increase the synthesis of secondary metabolites, and their beneficial effects depend on environmental factors and plant-related microorganisms. This article summarizes the impact and regulatory mechanisms of different microorganisms on the main secondary metabolic products of plants. We emphasize the mechanisms by which microorganisms regulate hormone levels, nutrient absorption, the supply of precursor substances, and enzyme and gene expression to promote the accumulation of plant secondary metabolites. In addition, the possible negative feedback regulation of microorganisms is discussed. The identification of additional unknown microbes and other driving factors affecting plant secondary metabolism is essential. The prospects for further analysis of medicinal plant genomes and the establishment of a genetic operation system for plant secondary metabolism research are proposed. This study provides new ideas for the use of microbial resources for biological synthesis research and the improvement of crop anti-inverse traits for the use of microbial resources.
植物次生代谢物具有广泛的药理活性和重要的生物学功能。它们既是植物受到病原体攻击时的防御反应，也是有价值的药物资源。微生物在调节植物次生代谢中的作用已得到广泛认可。添加特定的微生物可以增加次生代谢物的合成，其有益效果取决于环境因素和与植物相关的微生物。本文总结了不同微生物对植物主要次生代谢产物的影响和调控机制。我们强调了微生物调节激素水平、养分吸收、前体物质供应以及酶和基因表达以促进植物次生代谢物积累的机制。此外，还讨论了微生物可能存在的负反馈调节。需要进一步鉴定其他未知微生物和其他影响植物次生代谢的驱动因素。提出了进一步分析药用植物基因组和建立植物次生代谢遗传操作体系的研究前景。本研究为利用微生物资源进行生物合成研究以及利用微生物资源改善作物抗逆性提供了新的思路。
