Aziz Ahmed A, Aziz Muhammad A, Mehta Deep, Rashid Muhammad H
Department of Internal Medicine, Capital Health Regional Medical Center, Trenton, NJ, USA.
Department of Internal Medicine, Bronxcare Health System, New York City, New York, USA.
J Community Hosp Intern Med Perspect. 2024 Jan 12;14(1):95-97. doi: 10.55729/2000-9666.1291. eCollection 2024.
Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease that occurs in a bimodal age distribution in the second and fifth-sixth decade of life. The disease is more prevalent in females and presents with variable clinical manifestations ranging from being asymptomatic to acute liver failure. AIH is often overlooked and not worked up in elderly patients who present with liver failure. This can lead to increased morbidity and mortality in elderly patients. AIH should be considered as a differential diagnosis in patients who present with elevated transaminases regardless of age or gender as early recognition and treatment leads to improved outcomes. In this article, we present a unique case of AIH in a male patient in his eighth decade of life who presented with acute liver failure without any obvious cause and had no history of autoimmune diseases.
自身免疫性肝炎(AIH)是一种慢性炎症性肝病,发病年龄呈双峰分布,多见于第二个十年及第五至第六个十年。该疾病在女性中更为常见,临床表现多样,从无症状到急性肝衰竭不等。AIH在出现肝衰竭的老年患者中常被忽视且未得到充分检查。这可能导致老年患者的发病率和死亡率增加。对于出现转氨酶升高的患者,无论年龄或性别,都应将AIH视为鉴别诊断之一,因为早期识别和治疗可改善预后。在本文中,我们介绍了一例独特的AIH病例,患者为一名八十多岁的男性,出现急性肝衰竭,无任何明显病因,且无自身免疫性疾病史。