Department of Orthopaedic Surgery, University of Florence, Florence, Italy.
Articon Spezialpraxis Für Gelenkchirurgie, Berne, Switzerland.
Arch Orthop Trauma Surg. 2024 Sep;144(9):4059-4067. doi: 10.1007/s00402-024-05233-5. Epub 2024 Mar 14.
There is only limited literature available evaluating the preferable treatment for active mid-age or elderly patients presenting with a degenerative medial meniscus root tear (d-MMRT) with medial meniscal extrusion (MME) and early-phase radiographic osteoarthritis (OA), failing to provide solid evidence. The aim of this study was to evaluate early outcomes of medial unicompartimental arthroplasty (mUKA) in active patients presenting a d-MMRT with meniscal extrusion and mild radiographic OA of the knee. To prove this claim we hypothesized that (1) patients with a d-MMRT with initial grade 1-3 KL OA of the medial compartment of the knee present the same pre-operative symptoms as patients with an end-stage grade 4 K-L OA, and that (2) those patients with d-MMRT and low-grade OA achieve the same early clinical and functional outcomes when treated with mUKA compared to patients with end-stage medial OA.
We reviewed the prospectively collected data of 185 patients undergoing robotic-assisted image-based mUKA from January 2021 to July 2022 at a single Institution. We identified two different cohorts of non-consecutive patients: a group of 24 patients undergoing mUKA surgery following d-MMRT combined with K-L grades 1-3 OA (group 1), and a group of 161 patients who underwent mUKA but presenting with an end-stage bone-on-bone K-L grade 4 OA (group 2). Preoperative and postoperative clinical assessments at one-year follow-up included the Oxford Knee Score (OKS), 5-level EQ-5D version (EQ-5D-5L score), and a standard weight-bearing X-ray protocol. The paired t-test was used to compare clinical outcomes and radiologic values of the two cohorts and in-between the two cohorts. Statistical significance was set at p < 0.05.
The mean follow-up for group 1 was 16.4 ± 2.5 months, and the mean age at the time of operation was 63 ± 8.6 years with a mean time from diagnosis to intervention of 53 ± 47.5 days. Preoperative impairment was greater in group 1 compared to group 2, but with no significant difference. Postoperatively, both groups showed excellent mean outcomes at 1-year follow-up, with no significant difference. The mean preoperative HKA, mPTA, and LDFA were 176.3 ± 3.1, 88.1 ± 2.3, and 86.6 ± 1.7 respectively. The mean postoperative HKA, coronal femoral component angle, and coronal tibial component angle were 179.1 ± 2.6, 87.2 ± 2.3, and 87.2 ± 3.3. No difference was found between preoperative age, BMI, between the two cohorts.
Favorable early clinical outcomes were obtained after mUKA in active mid-age and elderly patients presenting with degenerative medial meniscus root tear and mild isolated medial OA. Patients with mild no bone-on-bone OA but with degenerative medial meniscus root tear and medial meniscal extrusion presented the same or worse pre-operative symptoms as patients with end-stage medial OA and benefit the same from mUKA.
目前仅有有限的文献评估对于表现为退行性内侧半月板根部撕裂(d-MMRT)伴内侧半月板突出(MME)和早期放射学骨关节炎(OA)的活跃中老年人患者的首选治疗方法,无法提供确凿的证据。本研究旨在评估内侧单室关节置换术(mUKA)在患有内侧半月板根部撕裂伴半月板突出和膝关节轻度放射学 OA 的活跃患者中的早期结果。为了证明这一说法,我们假设(1)内侧半月板根部撕裂伴初始 KL 分级 1-3 级 OA 的患者与终末期 KL 分级 4 级 OA 的患者具有相同的术前症状,(2)与终末期内侧 OA 患者相比,患有内侧半月板根部撕裂伴低等级 OA 的患者接受 mUKA 治疗可获得相同的早期临床和功能结果。
我们回顾了 2021 年 1 月至 2022 年 7 月在一家机构接受机器人辅助基于图像的 mUKA 的 185 例患者的前瞻性收集数据。我们确定了两个不同的非连续患者队列:一组 24 例患者接受 mUKA 手术治疗伴 d-MMRT 合并 KL 分级 1-3 OA(组 1),一组 161 例患者接受 mUKA 手术治疗,但伴终末期骨对骨 KL 分级 4 OA(组 2)。在术后 1 年随访时进行了术前和术后临床评估,包括牛津膝关节评分(OKS)、5 级 EQ-5D 版本(EQ-5D-5L 评分)和标准负重 X 射线方案。采用配对 t 检验比较两组和两组之间的临床结果和影像学值。统计学意义设为 p < 0.05。
组 1的平均随访时间为 16.4 ± 2.5 个月,手术时的平均年龄为 63 ± 8.6 岁,从诊断到干预的平均时间为 53 ± 47.5 天。与组 2相比,组 1术前损伤更严重,但无显著差异。术后两组在 1 年随访时均表现出良好的平均结果,无显著差异。术前平均 HKA、mPTA 和 LDFA 分别为 176.3 ± 3.1、88.1 ± 2.3 和 86.6 ± 1.7。术后平均 HKA、冠状股骨组件角和冠状胫骨组件角分别为 179.1 ± 2.6、87.2 ± 2.3 和 87.2 ± 3.3。术前年龄、BMI 在两组之间无差异。
在患有退行性内侧半月板根部撕裂和轻度孤立性内侧 OA 的活跃中老年人中,mUKA 后可获得良好的早期临床结果。伴有轻度非骨对骨 OA 但伴有退行性内侧半月板根部撕裂和内侧半月板突出的患者,其术前症状与终末期内侧 OA 患者相同或更差,但可从 mUKA 中获益相同。