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对于有症状的活跃患者,内侧单髁膝关节置换术治疗内侧半月板后根部撕裂伴半月板外突和轻度放射学骨关节炎具有良好的早期疗效。

Favorable early outcomes of medial unicompartimental knee arthroplasty in active patients presenting a degenerative medial meniscus root tear with meniscal extrusion and mild radiographic osteoarthritis.

机构信息

Department of Orthopaedic Surgery, University of Florence, Florence, Italy.

Articon Spezialpraxis Für Gelenkchirurgie, Berne, Switzerland.

出版信息

Arch Orthop Trauma Surg. 2024 Sep;144(9):4059-4067. doi: 10.1007/s00402-024-05233-5. Epub 2024 Mar 14.

Abstract

INTRODUCTION

There is only limited literature available evaluating the preferable treatment for active mid-age or elderly patients presenting with a degenerative medial meniscus root tear (d-MMRT) with medial meniscal extrusion (MME) and early-phase radiographic osteoarthritis (OA), failing to provide solid evidence. The aim of this study was to evaluate early outcomes of medial unicompartimental arthroplasty (mUKA) in active patients presenting a d-MMRT with meniscal extrusion and mild radiographic OA of the knee. To prove this claim we hypothesized that (1) patients with a d-MMRT with initial grade 1-3 KL OA of the medial compartment of the knee present the same pre-operative symptoms as patients with an end-stage grade 4 K-L OA, and that (2) those patients with d-MMRT and low-grade OA achieve the same early clinical and functional outcomes when treated with mUKA compared to patients with end-stage medial OA.

METHODS

We reviewed the prospectively collected data of 185 patients undergoing robotic-assisted image-based mUKA from January 2021 to July 2022 at a single Institution. We identified two different cohorts of non-consecutive patients: a group of 24 patients undergoing mUKA surgery following d-MMRT combined with K-L grades 1-3 OA (group 1), and a group of 161 patients who underwent mUKA but presenting with an end-stage bone-on-bone K-L grade 4 OA (group 2). Preoperative and postoperative clinical assessments at one-year follow-up included the Oxford Knee Score (OKS), 5-level EQ-5D version (EQ-5D-5L score), and a standard weight-bearing X-ray protocol. The paired t-test was used to compare clinical outcomes and radiologic values of the two cohorts and in-between the two cohorts. Statistical significance was set at p < 0.05.

RESULTS

The mean follow-up for group 1 was 16.4 ± 2.5 months, and the mean age at the time of operation was 63 ± 8.6 years with a mean time from diagnosis to intervention of 53 ± 47.5 days. Preoperative impairment was greater in group 1 compared to group 2, but with no significant difference. Postoperatively, both groups showed excellent mean outcomes at 1-year follow-up, with no significant difference. The mean preoperative HKA, mPTA, and LDFA were 176.3 ± 3.1, 88.1 ± 2.3, and 86.6 ± 1.7 respectively. The mean postoperative HKA, coronal femoral component angle, and coronal tibial component angle were 179.1 ± 2.6, 87.2 ± 2.3, and 87.2 ± 3.3. No difference was found between preoperative age, BMI, between the two cohorts.

CONCLUSIONS

Favorable early clinical outcomes were obtained after mUKA in active mid-age and elderly patients presenting with degenerative medial meniscus root tear and mild isolated medial OA. Patients with mild no bone-on-bone OA but with degenerative medial meniscus root tear and medial meniscal extrusion presented the same or worse pre-operative symptoms as patients with end-stage medial OA and benefit the same from mUKA.

摘要

简介

目前仅有有限的文献评估对于表现为退行性内侧半月板根部撕裂(d-MMRT)伴内侧半月板突出(MME)和早期放射学骨关节炎(OA)的活跃中老年人患者的首选治疗方法,无法提供确凿的证据。本研究旨在评估内侧单室关节置换术(mUKA)在患有内侧半月板根部撕裂伴半月板突出和膝关节轻度放射学 OA 的活跃患者中的早期结果。为了证明这一说法,我们假设(1)内侧半月板根部撕裂伴初始 KL 分级 1-3 级 OA 的患者与终末期 KL 分级 4 级 OA 的患者具有相同的术前症状,(2)与终末期内侧 OA 患者相比,患有内侧半月板根部撕裂伴低等级 OA 的患者接受 mUKA 治疗可获得相同的早期临床和功能结果。

方法

我们回顾了 2021 年 1 月至 2022 年 7 月在一家机构接受机器人辅助基于图像的 mUKA 的 185 例患者的前瞻性收集数据。我们确定了两个不同的非连续患者队列:一组 24 例患者接受 mUKA 手术治疗伴 d-MMRT 合并 KL 分级 1-3 OA(组 1),一组 161 例患者接受 mUKA 手术治疗,但伴终末期骨对骨 KL 分级 4 OA(组 2)。在术后 1 年随访时进行了术前和术后临床评估,包括牛津膝关节评分(OKS)、5 级 EQ-5D 版本(EQ-5D-5L 评分)和标准负重 X 射线方案。采用配对 t 检验比较两组和两组之间的临床结果和影像学值。统计学意义设为 p < 0.05。

结果

组 1的平均随访时间为 16.4 ± 2.5 个月,手术时的平均年龄为 63 ± 8.6 岁,从诊断到干预的平均时间为 53 ± 47.5 天。与组 2相比,组 1术前损伤更严重,但无显著差异。术后两组在 1 年随访时均表现出良好的平均结果,无显著差异。术前平均 HKA、mPTA 和 LDFA 分别为 176.3 ± 3.1、88.1 ± 2.3 和 86.6 ± 1.7。术后平均 HKA、冠状股骨组件角和冠状胫骨组件角分别为 179.1 ± 2.6、87.2 ± 2.3 和 87.2 ± 3.3。术前年龄、BMI 在两组之间无差异。

结论

在患有退行性内侧半月板根部撕裂和轻度孤立性内侧 OA 的活跃中老年人中,mUKA 后可获得良好的早期临床结果。伴有轻度非骨对骨 OA 但伴有退行性内侧半月板根部撕裂和内侧半月板突出的患者,其术前症状与终末期内侧 OA 患者相同或更差,但可从 mUKA 中获益相同。

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