Hospital de Pediatría S.A.M.I.C. Prof. Dr. Juan P. Garrahan, City of Buenos Aires, Argentina.
Arch Argent Pediatr. 2024 Oct 1;122(5):e202310224. doi: 10.5546/aap.2023-10224.eng. Epub 2024 Mar 21.
Scurvy is a disease caused by vitamin C deficiency. Although rare, in recent years, the number of scurvy cases in children with eating disorders has increased. Its manifestations are varied because vitamin C is a cofactor in numerous processes, such as collagen synthesis. The typical skin manifestations include petechiae, bruising, and hyperkeratosis. Mucosal involvement manifests as gingivitis with hypertrophy, bleeding, and loss of teeth. The diagnosis is based on clinical findings and may be confirmed by measuring plasma vitamin C levels. The objective of this study was to describe a cohort of patients diagnosed with scurvy in recent years, its clinical manifestations, and findings in relation to their eating behavior and neurodevelopmental disorders.
坏血病是一种由维生素 C 缺乏引起的疾病。尽管罕见，但近年来，饮食失调儿童的坏血病病例有所增加。其表现多种多样，因为维生素 C 是许多过程（如胶原蛋白合成）的辅助因子。典型的皮肤表现包括瘀点、瘀斑和过度角化。黏膜受累表现为牙龈增生、出血和牙齿脱落。诊断基于临床发现，可通过测量血浆维生素 C 水平来确认。本研究的目的是描述近年来诊断出的坏血病患者队列，以及他们的饮食行为和神经发育障碍与临床表现和发现的关系。
