Swanson Allison M, Hughey Lauren C
Department of Dermatology, University of Alabama at Birmingham, 1530 3rd Ave S, EFH 414, Birmingham, AL 35294-0009, USA.
Cutis. 2010 Oct;86(4):205-7.
Scurvy is a well-known disease of vitamin C deficiency that still occurs in industrialized countries. The clinical manifestations of follicular hyperkeratosis, perifollicular petechiae, corkscrew hairs, and easy bruising are due to defective collagen synthesis and can be mistaken for small vessel vasculitis. Populations at risk for development of scurvy include elderly patients, alcohol and drug users, individuals who follow restrictive diets or have eating disorders, patients with malabsorption, and individuals with mental illness. We report an acute case of scurvy presenting in the inpatient/hospital setting with clinical findings initially thought to represent vasculitis. A high index of suspicion for scurvy must be kept in the appropriate clinical context, and a thorough medical history and physical examination are vital to make the diagnosis.
坏血病是一种众所周知的维生素C缺乏症，在工业化国家仍有发生。毛囊角化过度、毛囊周围瘀点、螺旋状毛发和易瘀伤等临床表现是由于胶原蛋白合成缺陷所致，可能会被误诊为小血管血管炎。患坏血病风险较高的人群包括老年患者、酗酒和吸毒者、遵循限制性饮食或患有饮食失调症的人、吸收不良患者以及患有精神疾病的人。我们报告了一例在住院环境中出现的急性坏血病病例，其临床表现最初被认为是血管炎。在适当的临床背景下，必须高度怀疑坏血病，详细的病史和体格检查对于做出诊断至关重要。
