Ashmore Sarah, Kenton Kimberly, Das Deepanjana, Bretschneider C Emi
From the Section of Urogynecology and Reconstructive Pelvic Surgery, University of Chicago.
Division of Female Pelvic Medicine and Reconstructive Surgery, Northwestern Medicine, Chicago, IL.
Urogynecology (Phila). 2024 Mar 1;30(3):286-292. doi: 10.1097/SPV.0000000000001468.
Obesity is steadily increasing in the United States and is a risk factor for many medical and surgical complications. Literature is limited regarding obesity as an independent risk factor for perioperative complications after reconstructive pelvic surgery (RPS).
This study aimed to analyze the association of obesity on 30-day perioperative complications after RPS.
This was a database study comparing perioperative complications after RPS of obese versus nonobese patients using the American College of Surgeons National Surgical Quality Improvement Program. Patients who underwent surgery for uterovaginal or vaginal vault prolapse were selected, and perioperative outcomes were compared between obese and nonobese patients. Obesity was defined as a body mass index ≥30 (calculated as weight in kilograms divided by height in meters squared).
A total of 13,302 patients met the inclusion criteria and were included in this study; 4,815 patients were obese, whereas 8,487 were nonobese. The overall rate of any 30-day postoperative complication was 6.8%, and the rate of complications did not differ between groups. Superficial and organ space surgical site infections were significantly higher in the obese cohort, whereas nonobese patients were more likely to receive a blood transfusion. A multivariable logistic regression model was performed with variables that were statistically significant on bivariate analysis and deemed clinically significant. Variables included obesity, age, American Society of Anesthesiologists class, current smoker, diabetes, hypertension, operative time, colpopexy, and obliterative procedure. After controlling for potential confounding factors, obesity was not associated with any 30-day postoperative complications after pelvic organ prolapse surgery.
Obesity was not associated with 30-day postoperative complications after RPS after controlling for possible confounding variables.
肥胖在美国呈稳步上升趋势,是许多内科及外科并发症的危险因素。关于肥胖作为重建性盆腔手术(RPS)围手术期并发症独立危险因素的文献有限。
本研究旨在分析肥胖与RPS术后30天围手术期并发症之间的关联。
这是一项数据库研究,使用美国外科医师学会国家外科质量改进计划比较肥胖与非肥胖患者RPS术后的围手术期并发症。选取接受子宫阴道或阴道穹窿脱垂手术的患者,比较肥胖与非肥胖患者的围手术期结局。肥胖定义为体重指数≥30(体重以千克为单位,除以身高以米为单位的平方计算)。
共有13302例患者符合纳入标准并纳入本研究;4815例患者肥胖,而8487例患者非肥胖。术后30天任何并发症的总体发生率为6.8%,两组并发症发生率无差异。肥胖队列中表浅及器官腔隙手术部位感染显著更高,而非肥胖患者更可能接受输血。对双变量分析中有统计学意义且临床认为有意义的变量进行多变量逻辑回归模型分析。变量包括肥胖、年龄、美国麻醉医师协会分级、当前吸烟者、糖尿病、高血压、手术时间、阴道固定术和闭塞性手术。在控制潜在混杂因素后,肥胖与盆腔器官脱垂手术后30天的任何术后并发症均无关联。
在控制可能的混杂变量后,肥胖与RPS术后30天的术后并发症无关联。