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揭示革兰氏幽灵细胞：COVID-19 时代革兰氏染色的一个关键方面。

Unveiling Gram-Ghost Cells: A Crucial Aspect of Gram Staining in the COVID-19 Era.

作者信息

Hadano Yoshiro

机构信息

Division of Infection Control and Prevention, Shimane University Hospital, Izumo, JPN.

出版信息

Cureus. 2024 Feb 13;16(2):e54118. doi: 10.7759/cureus.54118. eCollection 2024 Feb.

DOI:10.7759/cureus.54118
PMID:38487138
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10938962/
Abstract

The term "Gram-ghost appearance" refers to mycobacteria's unique Gram staining characteristics. Recognizing as a potential pathogen in respiratory infections, especially in the elderly during the COVID-19 pandemic, is critical. This case highlights the pivotal role of Gram staining in diagnosis, particularly when COVID-19 tests consistently show negative results. Recognition of Gram-ghost bacilli facilitated prompt tuberculosis diagnosis, emphasizing the enduring diagnostic value of Gram staining, especially in the COVID-19 era.

摘要

“革兰氏幽灵样外观”一词指的是分枝杆菌独特的革兰氏染色特征。认识到分枝杆菌作为呼吸道感染尤其是在新冠疫情期间老年人呼吸道感染中的潜在病原体至关重要。该病例突出了革兰氏染色在诊断中的关键作用，特别是在新冠病毒检测持续呈阴性结果时。识别革兰氏幽灵样杆菌有助于及时诊断结核病，强调了革兰氏染色持久的诊断价值，尤其是在新冠时代。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f74f/10938962/19a43c196d39/cureus-0016-00000054118-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f74f/10938962/95a040f38b00/cureus-0016-00000054118-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f74f/10938962/72b272ba8887/cureus-0016-00000054118-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f74f/10938962/8b4c8cfd5291/cureus-0016-00000054118-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f74f/10938962/19a43c196d39/cureus-0016-00000054118-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f74f/10938962/95a040f38b00/cureus-0016-00000054118-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f74f/10938962/72b272ba8887/cureus-0016-00000054118-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f74f/10938962/8b4c8cfd5291/cureus-0016-00000054118-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f74f/10938962/19a43c196d39/cureus-0016-00000054118-i04.jpg

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本文引用的文献

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Int J Mycobacteriol. 2023 Oct-Dec;12(4):486-490. doi: 10.4103/ijmy.ijmy_188_23.
2
What is the impact of the COVID-19 pandemic on tuberculosis?新冠疫情对结核病有何影响？
Lancet Glob Health. 2023 Sep;11(9):e1323-e1324. doi: 10.1016/S2214-109X(23)00360-1.
3
The impact of COVID-19 on TB: a review of the data.COVID-19 对结核病的影响：数据回顾。
Int J Tuberc Lung Dis. 2021 Jun 1;25(6):436-446. doi: 10.5588/ijtld.21.0148.
4
Touch matters: COVID-19, physical examination, and 21st century general practice.触摸很重要：2019冠状病毒病、体格检查与21世纪的全科医疗
Br J Gen Pract. 2020 Nov 26;70(701):594-595. doi: 10.3399/bjgp20X713705. Print 2020 Dec.
5
Learning important clinical skills during junior residency in Japan: A Case of Gram Stain.在日本住院医师初级阶段学习重要的临床技能：革兰氏染色病例
J Gen Fam Med. 2020 May 29;21(3):33-34. doi: 10.1002/jgf2.317. eCollection 2020 May.
6
Gram-ghost bacilli.革兰氏阴性菌影杆菌
J Gen Fam Med. 2018 Oct 5;20(1):31-32. doi: 10.1002/jgf2.212. eCollection 2019 Jan.
7
Trends in incidence and mortality of tuberculosis in Japan: a population-based study, 1997-2016.日本结核病的发病率和死亡率趋势：一项基于人群的研究，1997 - 2016年
Epidemiol Infect. 2018 Nov 9;147:e38. doi: 10.1017/S095026881800290X.
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Gram-ghost cells.革兰氏阴性菌影细胞
BMJ Case Rep. 2013 Jan 31;2013:bcr2012008477. doi: 10.1136/bcr-2012-008477.
9
Gram-stain neutrality of Mycobacterium tuberculosis.
Am Rev Respir Dis. 1981 Apr;123(4 Pt 1):365-6. doi: 10.1164/arrd.1981.123.4.365.
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