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重症新型冠状病毒肺炎中因类固醇治疗导致播散性心内膜炎经药物治疗后的长期生存情况。

Long-term survival following medical management of endocarditis with dissemination as a consequence of steroid therapy in severe COVID-19 pneumonia.

作者信息

Kulirankal Kiran G, Mary Ann, Moni Merlin, Pillai Gopal S, Sathyapalan Dipu T

机构信息

Division of Infectious Diseases, Department of Internal Medicine, Amrita Institute of Medical Sciences, Kochi, India.

Department of Internal Medicine, Amrita Institute of Medical Sciences, Kochi, India.

出版信息

Med Mycol Case Rep. 2024 Mar 1;43:100638. doi: 10.1016/j.mmcr.2024.100638. eCollection 2024 Mar.

Abstract

A male in his 40's with no known comorbidities developed severe COVID-19 pneumonia and received a four-week course of methylprednisolone. The patient subsequently developed disseminated endocarditis, manifesting as multiple organ involvement including the heart, eyes, and brain. Despite the poor prognosis generally associated with fungal endocarditis, the patient survived following aggressive medical management with a combination of liposomal amphotericin b and voriconazole therapy and is now doing well for over two years and is off antifungal therapy for a year.

摘要

一名40多岁无已知合并症的男性患上了重症新型冠状病毒肺炎,并接受了为期四周的甲泼尼龙疗程。该患者随后发展为播散性心内膜炎,表现为包括心脏、眼睛和大脑在内的多器官受累。尽管真菌性心内膜炎通常预后较差,但该患者在接受脂质体两性霉素B和伏立康唑联合积极药物治疗后存活下来,目前情况良好已超过两年,且停用抗真菌治疗一年。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ff/10937298/7317a5a29894/gr1.jpg

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