• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Bisphosphonates for osteoporosis: from bench to clinic.

作者信息

Bellido Teresita

出版信息

J Clin Invest. 2024 Mar 15;134(6):e179942. doi: 10.1172/JCI179942.

DOI:10.1172/JCI179942
PMID:38488010
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10940084/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b6f/10940084/9fb274d8c75d/jci-134-179942-g197.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b6f/10940084/9fb274d8c75d/jci-134-179942-g197.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b6f/10940084/9fb274d8c75d/jci-134-179942-g197.jpg

相似文献

1
Bisphosphonates for osteoporosis: from bench to clinic.用于治疗骨质疏松症的双膦酸盐：从实验室到临床
J Clin Invest. 2024 Mar 15;134(6):e179942. doi: 10.1172/JCI179942.
2
[The successful development of bisphosphonates in the therapy of osteoporosis].[双膦酸盐类药物在骨质疏松症治疗中的成功研发]
Med Klin (Munich). 2006 Jun;101 Suppl 1:6-14. doi: 10.1007/s00063-006-9002-x.
3
Bisphosphonates for Postmenopausal Osteoporosis.用于绝经后骨质疏松症的双膦酸盐类药物。
JAMA. 2021 Jan 5;325(1):96. doi: 10.1001/jama.2020.2923.
4
Bisphosphonates for osteoporosis.用于治疗骨质疏松症的双膦酸盐类药物。
N Engl J Med. 2011 Feb 10;364(6):583; author reply 583-4. doi: 10.1056/NEJMc1014160.
5
Bisphosphonates for osteoporosis.用于治疗骨质疏松症的双膦酸盐类药物。
N Engl J Med. 2011 Feb 10;364(6):582-3; author reply 583-4. doi: 10.1056/NEJMc1014160.
6
Bridging the gap between evidence and practice in osteoporosis.弥合骨质疏松症领域证据与实践之间的差距。
Am J Health Syst Pharm. 2008 Feb 15;65(4):297. doi: 10.2146/ajhp070500.
7
Bisphosphonates for osteoporosis.用于治疗骨质疏松症的双膦酸盐类药物。
N Engl J Med. 2010 Nov 18;363(21):2027-35. doi: 10.1056/NEJMct1004903.
8
Prevention of postmenopausal osteoporosis and associated fractures: Clinical evaluation of the choice between estrogen and bisphosphonates.绝经后骨质疏松症及相关骨折的预防：雌激素与双膦酸盐选择的临床评估
Gynecol Endocrinol. 2008 Nov;24(11):601-9. doi: 10.1080/09513590802296245.
9
Practical guidance for the use of bisphosphonates in osteoporosis.骨质疏松症中双膦酸盐使用的实用指南。
Bone. 2020 Jul;136:115330. doi: 10.1016/j.bone.2020.115330. Epub 2020 Mar 25.
10
Bisphosphonates and colon cancer.双膦酸盐与结肠癌
Osteoporos Int. 2013 Mar;24(3):1139-40. doi: 10.1007/s00198-012-2078-7. Epub 2012 Jul 19.

引用本文的文献

1
Plasma metabolites mediate the causal effect of carbohydrate intake on bone mineral density.血浆代谢物介导碳水化合物摄入对骨密度的因果效应。
Medicine (Baltimore). 2025 Aug 1;104(31):e43608. doi: 10.1097/MD.0000000000043608.
2
Injectable magnesium-bisphosphonate MOF-based bone adhesive prevents excessive fibrosis for osteoporotic fracture repair.可注射的基于镁双膦酸盐金属有机框架的骨粘合剂可防止骨质疏松性骨折修复过程中出现过度纤维化。
Nat Commun. 2025 Jul 1;16(1):5679. doi: 10.1038/s41467-025-60853-8.
3
Nerve growth factor-loaded biomimetic prussian blue nanocomplexes for reversing osteoporosis via promoting osteoblast precursor cell proliferation and differentiation.

本文引用的文献

1
The Notch pathway regulates the bone gain induced by PTH anabolic signaling.Notch 通路调节 PTH 合成代谢信号诱导的骨量增加。
FASEB J. 2022 Mar;36(3):e22196. doi: 10.1096/fj.202101807R.
2
Targeting Notch Inhibitors to the Myeloma Bone Marrow Niche Decreases Tumor Growth and Bone Destruction without Gut Toxicity.靶向骨髓瘤骨髓基质细胞中的 Notch 抑制剂可减少肿瘤生长和骨质破坏而无肠道毒性。
Cancer Res. 2021 Oct 1;81(19):5102-5114. doi: 10.1158/0008-5472.CAN-21-0524. Epub 2021 Aug 4.
3
The osteocyte as a signaling cell.成骨细胞作为一种信号细胞。
负载神经生长因子的仿生普鲁士蓝纳米复合物通过促进成骨细胞前体细胞增殖和分化来逆转骨质疏松症
Mater Today Bio. 2025 May 22;32:101898. doi: 10.1016/j.mtbio.2025.101898. eCollection 2025 Jun.
4
Efficacy of acupuncture-related therapy for postmenopausal osteoporosis: a systematic review and network meta-analysis based on randomized controlled trials.针灸相关疗法治疗绝经后骨质疏松症的疗效：基于随机对照试验的系统评价和网状Meta分析
Front Med (Lausanne). 2025 Apr 9;12:1483819. doi: 10.3389/fmed.2025.1483819. eCollection 2025.
5
Comprehensive bioinformatics analysis reveals novel potential biomarkers associated with aging and mitochondria in osteoporosis.综合生物信息学分析揭示了骨质疏松症中与衰老和线粒体相关的新型潜在生物标志物。
Sci Rep. 2025 Jan 6;15(1):934. doi: 10.1038/s41598-024-84926-8.
6
Bone-targeting engineered milk-derived extracellular vesicles for MRI-assisted therapy of osteoporosis.用于骨质疏松症MRI辅助治疗的骨靶向工程化乳源细胞外囊泡
Regen Biomater. 2024 Sep 13;11:rbae112. doi: 10.1093/rb/rbae112. eCollection 2024.
7
Sophoraflavanone G Inhibits RANKL-Induced Osteoclastogenesis via MAPK/NF-κB Signaling Pathway.槐黄酮G通过MAPK/NF-κB信号通路抑制RANKL诱导的破骨细胞生成。
Mol Biotechnol. 2025 May;67(5):2085-2097. doi: 10.1007/s12033-024-01185-8. Epub 2024 May 23.
Physiol Rev. 2022 Jan 1;102(1):379-410. doi: 10.1152/physrev.00043.2020. Epub 2021 Aug 2.
4
Bisphosphonates for delivering drugs to bone.双膦酸盐类药物用于骨靶向给药。
Br J Pharmacol. 2021 May;178(9):2008-2025. doi: 10.1111/bph.15251. Epub 2021 Apr 10.
5
Targeting Bortezomib to Bone Increases Its Bone Anabolic Activity and Reduces Systemic Adverse Effects in Mice.将硼替佐米靶向至骨骼可增强其在小鼠体内的骨合成代谢活性并减少全身不良反应。
J Bone Miner Res. 2020 Feb;35(2):343-356. doi: 10.1002/jbmr.3889. Epub 2019 Nov 19.
6
Novel Radiolabeled Bisphosphonates for PET Diagnosis and Endoradiotherapy of Bone Metastases.用于骨转移正电子发射断层显像（PET）诊断及内放射治疗的新型放射性标记双膦酸盐
Pharmaceuticals (Basel). 2017 May 18;10(2):45. doi: 10.3390/ph10020045.
7
GGPS1 Mutation and Atypical Femoral Fractures with Bisphosphonates.GGPS1突变与双膦酸盐类药物所致非典型股骨骨折
N Engl J Med. 2017 May 4;376(18):1794-1795. doi: 10.1056/NEJMc1612804.
8
Design, Synthesis, and Antimicrobial Evaluation of a Novel Bone-Targeting Bisphosphonate-Ciprofloxacin Conjugate for the Treatment of Osteomyelitis Biofilms.一种用于治疗骨髓炎生物膜的新型骨靶向双膦酸盐-环丙沙星缀合物的设计、合成及抗菌评价
J Med Chem. 2017 Mar 23;60(6):2326-2343. doi: 10.1021/acs.jmedchem.6b01615. Epub 2017 Feb 13.
9
Osteocytic signalling pathways as therapeutic targets for bone fragility.骨细胞信号通路作为骨脆性的治疗靶点
Nat Rev Endocrinol. 2016 Oct;12(10):593-605. doi: 10.1038/nrendo.2016.71. Epub 2016 May 27.
10
Osteocyte-driven bone remodeling.成骨细胞驱动的骨重塑。
Calcif Tissue Int. 2014 Jan;94(1):25-34. doi: 10.1007/s00223-013-9774-y. Epub 2013 Sep 4.