澳大利亚城市废水中产超广谱β-内酰胺酶和耐碳青霉烯类大肠埃希菌的基因组特征。
Genomic characterization of extended-spectrum beta-lactamase-producing and carbapenem-resistant Escherichia coli from urban wastewater in Australia.
机构信息
School of Biological, Earth and Environmental Sciences, Centre for Marine Science and Innovation, UNSW Sydney, Sydney, New South Wales, Australia.
School of Population Health, UNSW Sydney, Sydney, New South Wales, Australia.
出版信息
Microbiologyopen. 2024 Apr;13(2):e1403. doi: 10.1002/mbo3.1403.
This study investigates extended-spectrum beta-lactamase-producing and carbapenem-resistant Escherichia coli isolates from Sydney's wastewater. These isolates exhibit resistance to critical antibiotics and harbor novel resistance mechanisms. The findings highlight the importance of wastewater-based surveillance in monitoring resistance beyond the clinical setting.
本研究调查了来自悉尼废水的产超广谱β-内酰胺酶和耐碳青霉烯类大肠埃希菌的分离株。这些分离株对关键抗生素表现出耐药性，并具有新的耐药机制。这些发现强调了基于废水的监测在临床环境之外监测耐药性的重要性。
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