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流感嗜血杆菌心内膜炎:病例报告及文献复习。

Haemophilus influenzae endocarditis: a case report and literature review.

机构信息

Internal Medicine, Greater Baltimore Medical Center, Towson, MD, USA.

Infectious Diseases, Greater Baltimore Medical Center, Towson, MD, USA.

出版信息

Infection. 2024 Aug;52(4):1621-1625. doi: 10.1007/s15010-024-02219-8. Epub 2024 Mar 15.

Abstract

INTRODUCTION

Haemophilus influenzae (HI) is an exceedingly rare cause of infective endocarditis (IE).

CASE PRESENTATION/METHODS: We present a case of a 90-year-old female diagnosed with HI-IE involving the native tricuspid valve in the absence of traditional risk factors for right-sided endocarditis. She was treated with a 5-week course of IV Ampicillin from negative cultures and suffered no complications. We also conducted a thorough literature review through PubMed and Google Scholar, which yielded a mere 15 reported cases of HI-IE.

RESULTS

Fourteen of the reported HI-IE cases included epidemiological data, showing no gender predominance. The mean age of the subjects was 39.5, with the mitral valve being the most implicated (64%) and tricuspid valve involvement being rare (21%).

CONCLUSION

Native tricuspid valve IE is an uncommon entity, especially in the absence of IV drug use. Haemophilus influenzae is an extremely rare cause of IE, with a literature review showing merely 15 reported cases. This article cites the 16th case of HI-IE published in the literature.

摘要

简介

流感嗜血杆菌(HI)是感染性心内膜炎(IE)的极罕见病因。

病例介绍/方法:我们报告了一例 90 岁女性患者,诊断为 HI-IE,涉及无传统右侧心内膜炎风险因素的原生三尖瓣。她接受了 5 周的静脉注射氨苄西林治疗,培养结果为阴性,且无并发症。我们还通过 PubMed 和 Google Scholar 进行了全面的文献回顾,仅发现了 15 例报道的 HI-IE 病例。

结果

报道的 14 例 HI-IE 病例包括流行病学数据,无明显性别优势。受试者的平均年龄为 39.5 岁,二尖瓣受累最常见(64%),三尖瓣受累罕见(21%)。

结论

原生三尖瓣 IE 是一种罕见的疾病,尤其是在没有静脉注射药物使用的情况下。流感嗜血杆菌是 IE 的极罕见病因,文献回顾显示仅有 15 例报道。本文报道了文献中第 16 例 HI-IE 病例。

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